Impact of personality traits on activities of daily living in patient-reported outcomes one and six months after total knee arthroplasty: a cohort study

Abstract Background Among the psychological factors, personality influences activities of daily living (ADL) in patient-reported outcomes (PROMs) following total knee arthroplasty (TKA). However, traditional personality assessments are often lengthy and challenging to implement in clinical settings....

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Main Authors: Keigo Nanjo, Takashi Ikeda, Ryutaku Kaneyama, Tomoko Sakai, Tetsuya Jinno
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Musculoskeletal Disorders
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Online Access:https://doi.org/10.1186/s12891-025-08861-z
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Summary:Abstract Background Among the psychological factors, personality influences activities of daily living (ADL) in patient-reported outcomes (PROMs) following total knee arthroplasty (TKA). However, traditional personality assessments are often lengthy and challenging to implement in clinical settings. Although the Ten-Item Personality Inventory (TIPI) can be administered quickly, its use in patients undergoing TKA remains unknown. This study aimed to explore the effect of personality traits measured using the TIPI on ADL in PROMs at one and six months post-TKA. Methods A cohort of 140 individuals undergoing bilateral or unilateral TKA was enrolled. The ADL subscale of the Knee Injury and Osteoarthritis Outcome Score (KOOS-ADL) and TIPI, which measures five traits (agreeableness, conscientiousness, extraversion, openness, and neuroticism), were evaluated one month preoperatively and one and six months postoperatively. Changes in the KOOS-ADL over time were assessed with a mixed-effects model for repeated measures, including personality traits that were significantly correlated with the KOOS-ADL as fixed effects. Participants were classified into two groups according to their neuroticism scores, following the study hypothesis. Group differences in recovery of the KOOS-ADL trajectory was also analyzed by a mixed-effects model. Results Of the 140 patients, 104 completed follow-up. Neuroticism was significantly correlated with the KOOS-ADL in all phases. The KOOS-ADL significantly improved one and six months after surgery compared with that at baseline. Higher neuroticism scores were significantly associated with lower KOOS-ADL scores (estimate = -2.55, P = 0.001). Patients in the neuroticism group also showed significantly lower KOOS-ADL scores than those in the non-neuroticism group (estimate = -5.56, P = 0.03), although the group-by-time interaction was not significant. Conclusions The TIPI is a useful tool for assessing personality traits preoperatively, especially neuroticism, which influence ADL in PROMs. Patients with high neuroticism may benefit from attentive follow-up that acknowledges the potential gap between subjective and objective outcomes. Clinical trial number Not applicable
ISSN:1471-2474