IPEX as a Result of Mutations in FOXP3
Immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare disorder caused by mutations in the FOXP3 gene that result in the defective development of CD4+CD25+ regulatory T cells which constitute an important T cell subset involved in immune homeostasis and protection a...
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Main Authors: | Hans J. J. van der Vliet, Edward E. Nieuwenhuis |
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Format: | Article |
Language: | English |
Published: |
Wiley
2007-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1155/2007/89017 |
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