IPEX as a Result of Mutations in FOXP3

Immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare disorder caused by mutations in the FOXP3 gene that result in the defective development of CD4+CD25+ regulatory T cells which constitute an important T cell subset involved in immune homeostasis and protection a...

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Bibliographic Details
Main Authors: Hans J. J. van der Vliet, Edward E. Nieuwenhuis
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2007/89017
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