Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study
Background. To assess the influence of a previous intestinal resection on postoperative complications for Crohn’s disease (CD). Methods. Data on patients with CD undergoing surgery in our department from January 2016 through December 2019 were retrospectively reviewed. Information collected included...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/2194382 |
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| _version_ | 1832547798191439872 |
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| author | Yantao Duan Yifan Liu Yousheng Li |
| author_facet | Yantao Duan Yifan Liu Yousheng Li |
| author_sort | Yantao Duan |
| collection | DOAJ |
| description | Background. To assess the influence of a previous intestinal resection on postoperative complications for Crohn’s disease (CD). Methods. Data on patients with CD undergoing surgery in our department from January 2016 through December 2019 were retrospectively reviewed. Information collected included demographic details, surgical data, and postoperative outcome. A cross-sectional study design was employed. Associations between postoperative complications and preoperative clinical indicators were further analyzed. Results. Of the 129 patients with CD studied, 62 patients (48.06%) underwent previous resection. These patients were more likely to be older (P=0.031), have longer disease duration (P=0.025), use less 5-aminosalicylic acid/sulfasalazine preoperatively (P=0.013), have lower body mass index (P=0.003), and have a higher American Society of Anesthesiologists (ASA) Physical Status Classification System score (P=0.043). Patients who had previous surgery had a longer duration of operation (P=0.003), greater estimated blood loss (P=0.001), and longer hospital stay (P<0.001) and were more inclined to develop postoperative complications (P=0.047), particularly anastomotic leak (P=0.021) and severe (Clavien–Dindo grade III/IV) complications (P=0.038). After multivariate analysis, previous intestinal resection (P=0.019), preoperative use of steroids (P=0.026), and ASA score of more than II (P<0.001) were determined to be the independent prognostic risk factors for postoperative complications. During the 30-day follow-up period, there was no postoperative mortality or readmission. Conclusions. Previous intestinal resection in patients with CD is an independent predictor of overall postoperative complications. |
| format | Article |
| id | doaj-art-a74c6ad36ad04894983ad5bddea569b5 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-a74c6ad36ad04894983ad5bddea569b52025-02-03T06:43:25ZengWileyGastroenterology Research and Practice1687-61211687-630X2020-01-01202010.1155/2020/21943822194382Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort StudyYantao Duan0Yifan Liu1Yousheng Li2Department of General Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaBackground. To assess the influence of a previous intestinal resection on postoperative complications for Crohn’s disease (CD). Methods. Data on patients with CD undergoing surgery in our department from January 2016 through December 2019 were retrospectively reviewed. Information collected included demographic details, surgical data, and postoperative outcome. A cross-sectional study design was employed. Associations between postoperative complications and preoperative clinical indicators were further analyzed. Results. Of the 129 patients with CD studied, 62 patients (48.06%) underwent previous resection. These patients were more likely to be older (P=0.031), have longer disease duration (P=0.025), use less 5-aminosalicylic acid/sulfasalazine preoperatively (P=0.013), have lower body mass index (P=0.003), and have a higher American Society of Anesthesiologists (ASA) Physical Status Classification System score (P=0.043). Patients who had previous surgery had a longer duration of operation (P=0.003), greater estimated blood loss (P=0.001), and longer hospital stay (P<0.001) and were more inclined to develop postoperative complications (P=0.047), particularly anastomotic leak (P=0.021) and severe (Clavien–Dindo grade III/IV) complications (P=0.038). After multivariate analysis, previous intestinal resection (P=0.019), preoperative use of steroids (P=0.026), and ASA score of more than II (P<0.001) were determined to be the independent prognostic risk factors for postoperative complications. During the 30-day follow-up period, there was no postoperative mortality or readmission. Conclusions. Previous intestinal resection in patients with CD is an independent predictor of overall postoperative complications.http://dx.doi.org/10.1155/2020/2194382 |
| spellingShingle | Yantao Duan Yifan Liu Yousheng Li Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study Gastroenterology Research and Practice |
| title | Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study |
| title_full | Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study |
| title_fullStr | Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study |
| title_full_unstemmed | Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study |
| title_short | Previous Intestinal Resection Is Associated with Postoperative Complications in Crohn’s Disease: A Cohort Study |
| title_sort | previous intestinal resection is associated with postoperative complications in crohn s disease a cohort study |
| url | http://dx.doi.org/10.1155/2020/2194382 |
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