Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature

Although malakoplakia has been reported to occur at various body sites, pancreatic malakoplakia with simultaneous colonic involvement is very rare. Lesions of malakoplakia can masquerade as tumor masses leading to unwanted resections. Nevertheless, malakoplakia can occur in association with frank ca...

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Main Authors: Surya Guha, Haiyan Liu
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2015/649136
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author Surya Guha
Haiyan Liu
author_facet Surya Guha
Haiyan Liu
author_sort Surya Guha
collection DOAJ
description Although malakoplakia has been reported to occur at various body sites, pancreatic malakoplakia with simultaneous colonic involvement is very rare. Lesions of malakoplakia can masquerade as tumor masses leading to unwanted resections. Nevertheless, malakoplakia can occur in association with frank carcinomas, especially in the colon. By reporting a case of pancreatic malakoplakia diagnosed by fine needle aspiration cytology, this paper aims to describe cytologic features of malakoplakia and to further review findings from previous reported cases of pancreatic malakoplakia in the literature. With advances in minimally invasive, image-guided aspiration technologies, cytomorphological analyses can diagnose lesions of malakoplakia. This may help avoid surgeries that would have otherwise been carried out due to a misleading impression of tumor. However challenges remain as to the further management of patients diagnosed with this condition. More studies are necessary to determine the probability of malignancies arising in association with malakoplakia, in order to devise appropriate treatment protocols.
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spelling doaj-art-a74ac03c3809479f8803cd44448d4a382025-02-03T06:44:44ZengWileyCase Reports in Pathology2090-67812090-679X2015-01-01201510.1155/2015/649136649136Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the LiteratureSurya Guha0Haiyan Liu1Geisinger Medical Center, 100 North Academy Avenue, Danville, PA 17821, USAGeisinger Medical Center, 100 North Academy Avenue, Danville, PA 17821, USAAlthough malakoplakia has been reported to occur at various body sites, pancreatic malakoplakia with simultaneous colonic involvement is very rare. Lesions of malakoplakia can masquerade as tumor masses leading to unwanted resections. Nevertheless, malakoplakia can occur in association with frank carcinomas, especially in the colon. By reporting a case of pancreatic malakoplakia diagnosed by fine needle aspiration cytology, this paper aims to describe cytologic features of malakoplakia and to further review findings from previous reported cases of pancreatic malakoplakia in the literature. With advances in minimally invasive, image-guided aspiration technologies, cytomorphological analyses can diagnose lesions of malakoplakia. This may help avoid surgeries that would have otherwise been carried out due to a misleading impression of tumor. However challenges remain as to the further management of patients diagnosed with this condition. More studies are necessary to determine the probability of malignancies arising in association with malakoplakia, in order to devise appropriate treatment protocols.http://dx.doi.org/10.1155/2015/649136
spellingShingle Surya Guha
Haiyan Liu
Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
Case Reports in Pathology
title Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
title_full Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
title_fullStr Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
title_full_unstemmed Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
title_short Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
title_sort malakoplakia of the pancreas with simultaneous colon involvement case report and review of the literature
url http://dx.doi.org/10.1155/2015/649136
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