Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik
Hyperglycemic is common in traumatic brain injury (TBI). Centella asiatica (CA) has antioxidant and antihyperglycemic effects. Objective: To determine the effect of CA on GDS in rat with TBI models. Methods: true experimental design with post test only controlled group design. The study used 35 expe...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universitas Andalas
2023-02-01
|
| Series: | Majalah Kedokteran Andalas |
| Subjects: | |
| Online Access: | https://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1063 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850194862098350080 |
|---|---|
| author | Nafiisah Nafiisah |
| author_facet | Nafiisah Nafiisah |
| author_sort | Nafiisah Nafiisah |
| collection | DOAJ |
| description | Hyperglycemic is common in traumatic brain injury (TBI). Centella asiatica (CA) has antioxidant and antihyperglycemic effects. Objective: To determine the effect of CA on GDS in rat with TBI models. Methods: true experimental design with post test only controlled group design. The study used 35 experimental animals randomly divided into 5 groups. P1 was healthy rat, P2 was sick rat, P3, P4, and P5 were the model group TBI and given CA with dose of 150, 300, and 600 mg/kgbb/day. Administration of CA which was given orally and measurement of GDS levels was done after 7 days of treatment. The statistical test used the One Way ANOVA test, the Post Hoc LSD test. Results: Mean GDS at P1 = 94.78 ± 42.47; P2 = 90.97 ± 06.44; P3 = 110.21 ± 3.70; P4 = 122.35 ± 4.91; and P5 = 128.57 ± 3.90. The One Way ANOVA test results show the fact that there is a statistically significant population (p = 0.000). The results of the LSD Post Hoc Test showed that there was a difference between P1 and P3, P4 and P5; P2 with P3, P4 and P5; P3 to P5. Conclusion: the effect of CA on GDS levels in rat with TBI models |
| format | Article |
| id | doaj-art-a74ab61b7e554b67a3fc4485a9fa68c7 |
| institution | OA Journals |
| issn | 0126-2092 2442-5230 |
| language | English |
| publishDate | 2023-02-01 |
| publisher | Universitas Andalas |
| record_format | Article |
| series | Majalah Kedokteran Andalas |
| spelling | doaj-art-a74ab61b7e554b67a3fc4485a9fa68c72025-08-20T02:13:53ZengUniversitas AndalasMajalah Kedokteran Andalas0126-20922442-52302023-02-0146114514910.25077/mka.v46.i1.p145-149.2023700Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatikNafiisah Nafiisah0Jenderal Soedirman UniversityHyperglycemic is common in traumatic brain injury (TBI). Centella asiatica (CA) has antioxidant and antihyperglycemic effects. Objective: To determine the effect of CA on GDS in rat with TBI models. Methods: true experimental design with post test only controlled group design. The study used 35 experimental animals randomly divided into 5 groups. P1 was healthy rat, P2 was sick rat, P3, P4, and P5 were the model group TBI and given CA with dose of 150, 300, and 600 mg/kgbb/day. Administration of CA which was given orally and measurement of GDS levels was done after 7 days of treatment. The statistical test used the One Way ANOVA test, the Post Hoc LSD test. Results: Mean GDS at P1 = 94.78 ± 42.47; P2 = 90.97 ± 06.44; P3 = 110.21 ± 3.70; P4 = 122.35 ± 4.91; and P5 = 128.57 ± 3.90. The One Way ANOVA test results show the fact that there is a statistically significant population (p = 0.000). The results of the LSD Post Hoc Test showed that there was a difference between P1 and P3, P4 and P5; P2 with P3, P4 and P5; P3 to P5. Conclusion: the effect of CA on GDS levels in rat with TBI modelshttps://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1063biomedical sciences |
| spellingShingle | Nafiisah Nafiisah Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik Majalah Kedokteran Andalas biomedical sciences |
| title | Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik |
| title_full | Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik |
| title_fullStr | Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik |
| title_full_unstemmed | Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik |
| title_short | Pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus (rattus novergicus) model cedera otak traumatik |
| title_sort | pengaruh pemberian ekstrak centella asiatica terhadap kadar gula darah sewaktu tikus rattus novergicus model cedera otak traumatik |
| topic | biomedical sciences |
| url | https://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1063 |
| work_keys_str_mv | AT nafiisahnafiisah pengaruhpemberianekstrakcentellaasiaticaterhadapkadarguladarahsewaktutikusrattusnovergicusmodelcederaotaktraumatik |