Rationale and Design of a Randomized, Open‐Label, Parallel‐Group Study of Esaxerenone Versus Angiotensin Receptor Blockers in Older Patients With Uncontrolled Hypertension on Calcium Channel Blocker Monotherapy (ESCORT‐HT)

Rationale and Design of a Randomized, Open‐Label, Parallel‐Group Study of Esaxerenone Versus Angiotensin Receptor Blockers in Older Patients With Uncontrolled Hypertension on Calcium Channel Blocker Monotherapy (ESCORT‐HT)

ABSTRACT Angiotensin II receptor blockers (ARBs) and calcium channel blockers (CCBs) are commonly prescribed as first‐ and second‐line treatments for older Japanese patients with hypertension. However, due to age‐related decline in renin activity, the effectiveness of ARBs may decrease. This highlig...

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Main Authors: Kazuomi Kario, Tomohiro Katsuya, Tatsuo Shimosawa, Takashi Taguchi, Ayumi Tanabe, Mitsuru Ohishi, the ESCORT‐HT investigators
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:The Journal of Clinical Hypertension
Subjects:
angiotensin II receptor blockers
esaxerenone
hypertension
mineralocorticoid receptor blockers
randomized comparative study
Online Access:https://doi.org/10.1111/jch.14947
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https://doi.org/10.1111/jch.14947

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