Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score
The objective was to develop a score, to stratify patients with acute cholecystitis into high, intermediate, or low probability of gangrenous cholecystitis. The probability of gangrenous cholecystitis (score) was derived from a logistic regression of a clinical and pathological review of 245 patien...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2010/901739 |
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| author | Wael N. Yacoub Mikael Petrosyan Indu Sehgal Yanling Ma Parakrama Chandrasoma Rodney J. Mason |
| author_facet | Wael N. Yacoub Mikael Petrosyan Indu Sehgal Yanling Ma Parakrama Chandrasoma Rodney J. Mason |
| author_sort | Wael N. Yacoub |
| collection | DOAJ |
| description | The objective was to develop a score, to stratify patients with acute cholecystitis into high, intermediate, or low probability of gangrenous cholecystitis. The probability of gangrenous cholecystitis (score) was derived from a logistic regression of a clinical and pathological review of 245 patients undergoing urgent cholecystectomy. Sixty-eight patients had gangrenous inflammation, 132 acute, and 45 no inflammation. The score comprised of: age > 45 years (1 point), heart rate > 90 beats/min (1 point), male (2 points), Leucocytosis > 13,000/mm3 (1.5 points), and ultrasound gallbladder wall thickness > 4.5 mm (1 point). The prevalence of gangrenous cholecystitis was 13% in the low-probability (0–2 points), 33% in the intermediate-probability (2–4.5 points), and 87% in the high probability category (>4.5 points). A cutoff score of 2 identified 31 (69%) patients with no acute inflammation (PPV 90%). This scoring system can prioritize patients for emergent cholecystectomy based on their expected pathology. |
| format | Article |
| id | doaj-art-a728c956dfe343929925a891669ac204 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-a728c956dfe343929925a891669ac2042025-02-03T01:09:03ZengWileyGastroenterology Research and Practice1687-61211687-630X2010-01-01201010.1155/2010/901739901739Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple ScoreWael N. Yacoub0Mikael Petrosyan1Indu Sehgal2Yanling Ma3Parakrama Chandrasoma4Rodney J. Mason5Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USADepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USADepartment of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USADepartment of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USADepartment of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USADepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USAThe objective was to develop a score, to stratify patients with acute cholecystitis into high, intermediate, or low probability of gangrenous cholecystitis. The probability of gangrenous cholecystitis (score) was derived from a logistic regression of a clinical and pathological review of 245 patients undergoing urgent cholecystectomy. Sixty-eight patients had gangrenous inflammation, 132 acute, and 45 no inflammation. The score comprised of: age > 45 years (1 point), heart rate > 90 beats/min (1 point), male (2 points), Leucocytosis > 13,000/mm3 (1.5 points), and ultrasound gallbladder wall thickness > 4.5 mm (1 point). The prevalence of gangrenous cholecystitis was 13% in the low-probability (0–2 points), 33% in the intermediate-probability (2–4.5 points), and 87% in the high probability category (>4.5 points). A cutoff score of 2 identified 31 (69%) patients with no acute inflammation (PPV 90%). This scoring system can prioritize patients for emergent cholecystectomy based on their expected pathology.http://dx.doi.org/10.1155/2010/901739 |
| spellingShingle | Wael N. Yacoub Mikael Petrosyan Indu Sehgal Yanling Ma Parakrama Chandrasoma Rodney J. Mason Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score Gastroenterology Research and Practice |
| title | Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score |
| title_full | Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score |
| title_fullStr | Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score |
| title_full_unstemmed | Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score |
| title_short | Prediction of Patients with Acute Cholecystitis Requiring Emergent Cholecystectomy: A Simple Score |
| title_sort | prediction of patients with acute cholecystitis requiring emergent cholecystectomy a simple score |
| url | http://dx.doi.org/10.1155/2010/901739 |
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