Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer

Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, e...

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Main Authors: Rui Dong, Jing Wang, Ruiqi Guan, Jianwei Sun, Ping Jin, Junling Shen
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/14/1/104
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author Rui Dong
Jing Wang
Ruiqi Guan
Jianwei Sun
Ping Jin
Junling Shen
author_facet Rui Dong
Jing Wang
Ruiqi Guan
Jianwei Sun
Ping Jin
Junling Shen
author_sort Rui Dong
collection DOAJ
description Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer.
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institution Kabale University
issn 2076-3921
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publishDate 2025-01-01
publisher MDPI AG
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series Antioxidants
spelling doaj-art-a70d3f5ec3514be2967db63a930b7b692025-01-24T13:19:29ZengMDPI AGAntioxidants2076-39212025-01-0114110410.3390/antiox14010104Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast CancerRui Dong0Jing Wang1Ruiqi Guan2Jianwei Sun3Ping Jin4Junling Shen5Yunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaBreast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer.https://www.mdpi.com/2076-3921/14/1/104oxidative stressbreast cancerdrug resistancetherapeutic strategiesreactive oxygen species (ROS)
spellingShingle Rui Dong
Jing Wang
Ruiqi Guan
Jianwei Sun
Ping Jin
Junling Shen
Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
Antioxidants
oxidative stress
breast cancer
drug resistance
therapeutic strategies
reactive oxygen species (ROS)
title Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
title_full Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
title_fullStr Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
title_full_unstemmed Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
title_short Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
title_sort role of oxidative stress in the occurrence development and treatment of breast cancer
topic oxidative stress
breast cancer
drug resistance
therapeutic strategies
reactive oxygen species (ROS)
url https://www.mdpi.com/2076-3921/14/1/104
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AT jingwang roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer
AT ruiqiguan roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer
AT jianweisun roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer
AT pingjin roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer
AT junlingshen roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer