Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer
Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, e...
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Format: | Article |
Language: | English |
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MDPI AG
2025-01-01
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Series: | Antioxidants |
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Online Access: | https://www.mdpi.com/2076-3921/14/1/104 |
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author | Rui Dong Jing Wang Ruiqi Guan Jianwei Sun Ping Jin Junling Shen |
author_facet | Rui Dong Jing Wang Ruiqi Guan Jianwei Sun Ping Jin Junling Shen |
author_sort | Rui Dong |
collection | DOAJ |
description | Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer. |
format | Article |
id | doaj-art-a70d3f5ec3514be2967db63a930b7b69 |
institution | Kabale University |
issn | 2076-3921 |
language | English |
publishDate | 2025-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Antioxidants |
spelling | doaj-art-a70d3f5ec3514be2967db63a930b7b692025-01-24T13:19:29ZengMDPI AGAntioxidants2076-39212025-01-0114110410.3390/antiox14010104Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast CancerRui Dong0Jing Wang1Ruiqi Guan2Jianwei Sun3Ping Jin4Junling Shen5Yunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, ChinaBreast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer.https://www.mdpi.com/2076-3921/14/1/104oxidative stressbreast cancerdrug resistancetherapeutic strategiesreactive oxygen species (ROS) |
spellingShingle | Rui Dong Jing Wang Ruiqi Guan Jianwei Sun Ping Jin Junling Shen Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer Antioxidants oxidative stress breast cancer drug resistance therapeutic strategies reactive oxygen species (ROS) |
title | Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer |
title_full | Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer |
title_fullStr | Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer |
title_full_unstemmed | Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer |
title_short | Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer |
title_sort | role of oxidative stress in the occurrence development and treatment of breast cancer |
topic | oxidative stress breast cancer drug resistance therapeutic strategies reactive oxygen species (ROS) |
url | https://www.mdpi.com/2076-3921/14/1/104 |
work_keys_str_mv | AT ruidong roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer AT jingwang roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer AT ruiqiguan roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer AT jianweisun roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer AT pingjin roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer AT junlingshen roleofoxidativestressintheoccurrencedevelopmentandtreatmentofbreastcancer |