Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications
Chitosan, a multifaceted amino polysaccharide biopolymer derived from chitin, has extensive antibacterial efficacy against diverse pathogenic microorganisms, including both Gram-negative and Gram-positive bacteria, in addition to fungi. Over the course of the last several decades, chitosan nanoparti...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/15/2/126 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832587810622668800 |
|---|---|
| author | Emir Akdaşçi Hatice Duman Furkan Eker Mikhael Bechelany Sercan Karav |
| author_facet | Emir Akdaşçi Hatice Duman Furkan Eker Mikhael Bechelany Sercan Karav |
| author_sort | Emir Akdaşçi |
| collection | DOAJ |
| description | Chitosan, a multifaceted amino polysaccharide biopolymer derived from chitin, has extensive antibacterial efficacy against diverse pathogenic microorganisms, including both Gram-negative and Gram-positive bacteria, in addition to fungi. Over the course of the last several decades, chitosan nanoparticles (NPs), which are polymeric and bio-based, have garnered a great deal of interest as efficient antibacterial agents. This is mostly due to the fact that they are used in a wide variety of applications, including medical treatments, food, chemicals, and agricultural products. Within the context of the antibacterial mechanism of chitosan and chitosan NPs, we present a review that provides an overview of the synthesis methods, including novel procedures, and compiles the applications that have been developed in the field of biomedicine. These applications include wound healing, drug delivery, dental treatment, water purification, agriculture, and food preservation. In addition to this, we focus on the mechanisms of action and the factors that determine the antibacterial activity of chitosan and its derivatives. In conjunction with this line of inquiry, researchers are strongly urged to concentrate their efforts on developing novel and ground-breaking applications of chitosan NPs. |
| format | Article |
| id | doaj-art-a6e1f557703747b78267d8799c2dddb7 |
| institution | Kabale University |
| issn | 2079-4991 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-a6e1f557703747b78267d8799c2dddb72025-01-24T13:44:14ZengMDPI AGNanomaterials2079-49912025-01-0115212610.3390/nano15020126Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial ApplicationsEmir Akdaşçi0Hatice Duman1Furkan Eker2Mikhael Bechelany3Sercan Karav4Department of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeEuropean Institute for Membranes (IEM), UMR-5635, University Montpellier, ENSCM, CNRS, Place Eugène Bataillon, CEDEX 5, F-34095 Montpellier, FranceDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeChitosan, a multifaceted amino polysaccharide biopolymer derived from chitin, has extensive antibacterial efficacy against diverse pathogenic microorganisms, including both Gram-negative and Gram-positive bacteria, in addition to fungi. Over the course of the last several decades, chitosan nanoparticles (NPs), which are polymeric and bio-based, have garnered a great deal of interest as efficient antibacterial agents. This is mostly due to the fact that they are used in a wide variety of applications, including medical treatments, food, chemicals, and agricultural products. Within the context of the antibacterial mechanism of chitosan and chitosan NPs, we present a review that provides an overview of the synthesis methods, including novel procedures, and compiles the applications that have been developed in the field of biomedicine. These applications include wound healing, drug delivery, dental treatment, water purification, agriculture, and food preservation. In addition to this, we focus on the mechanisms of action and the factors that determine the antibacterial activity of chitosan and its derivatives. In conjunction with this line of inquiry, researchers are strongly urged to concentrate their efforts on developing novel and ground-breaking applications of chitosan NPs.https://www.mdpi.com/2079-4991/15/2/126chitosanchitosan nanoparticlesantibacterialdrug deliveryagriculturenanocomposites |
| spellingShingle | Emir Akdaşçi Hatice Duman Furkan Eker Mikhael Bechelany Sercan Karav Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications Nanomaterials chitosan chitosan nanoparticles antibacterial drug delivery agriculture nanocomposites |
| title | Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications |
| title_full | Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications |
| title_fullStr | Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications |
| title_full_unstemmed | Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications |
| title_short | Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications |
| title_sort | chitosan and its nanoparticles a multifaceted approach to antibacterial applications |
| topic | chitosan chitosan nanoparticles antibacterial drug delivery agriculture nanocomposites |
| url | https://www.mdpi.com/2079-4991/15/2/126 |
| work_keys_str_mv | AT emirakdasci chitosananditsnanoparticlesamultifacetedapproachtoantibacterialapplications AT haticeduman chitosananditsnanoparticlesamultifacetedapproachtoantibacterialapplications AT furkaneker chitosananditsnanoparticlesamultifacetedapproachtoantibacterialapplications AT mikhaelbechelany chitosananditsnanoparticlesamultifacetedapproachtoantibacterialapplications AT sercankarav chitosananditsnanoparticlesamultifacetedapproachtoantibacterialapplications |