The CCR4-NOT complex is implicated in the viability of aneuploid yeasts.

The CCR4-NOT complex is implicated in the viability of aneuploid yeasts.

To identify the genes required to sustain aneuploid viability, we screened a deletion library of non-essential genes in the fission yeast Schizosaccharomyces pombe, in which most types of aneuploidy are eventually lethal to the cell. Aneuploids remain viable for a period of time and can form colonie...

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Main Authors: Yoshie Tange, Atsushi Kurabayashi, Bunshiro Goto, Kwang-Lae Hoe, Dong-Uk Kim, Han-Oh Park, Jacqueline Hayles, Yuji Chikashige, Chihiro Tsutumi, Yasushi Hiraoka, Fumiaki Yamao, Paul Nurse, Osami Niwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002776&type=printable
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