Mendelian randomization analysis of inflammatory biomarkers and hepatocellular carcinoma risk: genetic causality and single-cell transcriptomics
Abstract Background The causal relationship between inflammatory biomarkers and hepatocellular carcinoma (HCC) risk remains unclear. This study aimed to investigate the causal associations between various inflammation-related biomarkers and HCC risk using Mendelian randomization (MR) analysis, compl...
Saved in:
| Main Authors: | GuangXin Shao, Xiao Yun, Hongyue Xie, Beicheng Sun |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-03357-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Genetically predicted immune cells mediates the association between hepatocellular carcinoma and inflammatory proteins: a Mendelian randomization study
by: Yunlan Wang, et al.
Published: (2025-06-01) -
Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis
by: Ma J, et al.
Published: (2025-07-01) -
Integration of single-cell sequencing and mendelian randomization reveals novel causal pathways between monocytes and hepatocellular carcinoma
by: Jiang Yu, et al.
Published: (2025-04-01) -
The Causal Effects Between Circulating Inflammatory Proteins and Osteoarthritis: A Mendelian Randomization and Transcriptomic Analysis
by: Lin S, et al.
Published: (2025-07-01) -
Mutual causal effects between immune cells and hepatocellular carcinoma: a Mendelian randomization study
by: Zheng Wang, et al.
Published: (2025-01-01)