CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer’s disease patients

CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer’s disease patients

Abstract Background Amyloid-related imaging abnormalities (ARIA) are a common and potentially dangerous side effect in anti-amyloid therapies, creating a need for tools to assess ARIA risk. Several patient factors have been linked to ARIA; namely the presence of microbleeds (MBL+), APOE E4 carriersh...

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Main Authors: Marlies Oosthoek, Everard G.B. Vijverberg, Elena R. Blujdea, Sjors G.J.G. In’t Veld, Martín Pucheu Avilés, Sára E. Zsadanyi, Yanaika S. Hok-A-Hin, Allerdien Visser, Wiesje M. van der Flier, Frederik Barkhof, Marta del Campo, Martijn C. Schut, Alexandre Bejanin, Daniel Alcolea, Charlotte E. Teunissen, Lisa Vermunt
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
ARIA
Biomarker
Risk
Online Access:https://doi.org/10.1186/s13195-025-01799-3
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