Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma

Introduction. Tension pneumocephalus (TP) is a very rare complication related to radiotherapy for nasopharyngeal carcinoma (NPC). Case Presentation. A 46-year-old man was admitted to the hospital with an altered mental status and aqueous rhinorrhea for several hours of evolution. The computed tomogr...

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Main Authors: Esther Jimenez-Jimenez, Sebastià Sabater Martí, M. Victoria Villas
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/327380
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author Esther Jimenez-Jimenez
Sebastià Sabater Martí
M. Victoria Villas
author_facet Esther Jimenez-Jimenez
Sebastià Sabater Martí
M. Victoria Villas
author_sort Esther Jimenez-Jimenez
collection DOAJ
description Introduction. Tension pneumocephalus (TP) is a very rare complication related to radiotherapy for nasopharyngeal carcinoma (NPC). Case Presentation. A 46-year-old man was admitted to the hospital with an altered mental status and aqueous rhinorrhea for several hours of evolution. The computed tomography (CT) scan showed TP, a defect in the skull base and nasocranial fistula. The patient was receiving a second course of radiotherapy for local relapse. With medical treatment the patient recovered neurological status but died two days later. Discussion. In our knowledge, only 4 cases with similar characteristics have been reported in the literature. This is the first case report of TP during radiotherapy. TP was an abrupt and rapid process with neurological impairment for hours of evolution without suspicious osteoradionecrosis (OR) in previous scan images. The defect in the skull base could be due to a rapid disappearance of the tumor. The appearance of aqueous rhinorrhea and neurological symptoms must be viewed as signs of alarm.
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institution Kabale University
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spelling doaj-art-a6b6f8aaf6d94c0fa8ed12392d309b982025-02-03T01:01:37ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/327380327380Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal CarcinomaEsther Jimenez-Jimenez0Sebastià Sabater Martí1M. Victoria Villas2Radiation Oncology Department, Hospital Universitari Son Espases de Palma de Mallorca, Palma Health Research Institute (IdIsPa), 07005 Palma de Mallorca, SpainRadiation Oncology Department, Complejo Hospitalario Universitario de Albacete, 02006 Albacete, SpainRadiation Oncology Department, Complejo Hospitalario Universitario de Albacete, 02006 Albacete, SpainIntroduction. Tension pneumocephalus (TP) is a very rare complication related to radiotherapy for nasopharyngeal carcinoma (NPC). Case Presentation. A 46-year-old man was admitted to the hospital with an altered mental status and aqueous rhinorrhea for several hours of evolution. The computed tomography (CT) scan showed TP, a defect in the skull base and nasocranial fistula. The patient was receiving a second course of radiotherapy for local relapse. With medical treatment the patient recovered neurological status but died two days later. Discussion. In our knowledge, only 4 cases with similar characteristics have been reported in the literature. This is the first case report of TP during radiotherapy. TP was an abrupt and rapid process with neurological impairment for hours of evolution without suspicious osteoradionecrosis (OR) in previous scan images. The defect in the skull base could be due to a rapid disappearance of the tumor. The appearance of aqueous rhinorrhea and neurological symptoms must be viewed as signs of alarm.http://dx.doi.org/10.1155/2014/327380
spellingShingle Esther Jimenez-Jimenez
Sebastià Sabater Martí
M. Victoria Villas
Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma
Case Reports in Oncological Medicine
title Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma
title_full Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma
title_fullStr Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma
title_full_unstemmed Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma
title_short Tension Pneumocephalus Related to Radiotherapy for Nasopharyngeal Carcinoma
title_sort tension pneumocephalus related to radiotherapy for nasopharyngeal carcinoma
url http://dx.doi.org/10.1155/2014/327380
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