Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies

Objectives. This paper offers a critical review of published information on the imaging strategies used for diagnosing bisphosphonate-associated osteonecrosis of the jaw (BRONJ) in patients taking intravenous bisphosphonates, pointing at the different methodologies and results of existing literature...

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Main Authors: André Ferreira Leite, Fernanda dos Santos Ogata, Nilce Santos de Melo, Paulo Tadeu de Souza Figueiredo
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2014/784348
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author André Ferreira Leite
Fernanda dos Santos Ogata
Nilce Santos de Melo
Paulo Tadeu de Souza Figueiredo
author_facet André Ferreira Leite
Fernanda dos Santos Ogata
Nilce Santos de Melo
Paulo Tadeu de Souza Figueiredo
author_sort André Ferreira Leite
collection DOAJ
description Objectives. This paper offers a critical review of published information on the imaging strategies used for diagnosing bisphosphonate-associated osteonecrosis of the jaw (BRONJ) in patients taking intravenous bisphosphonates, pointing at the different methodologies and results of existing literature. Methods. Electronic literature search was performed in order to identify as many quantitative studies that discussed the imaging findings of BRONJ up to February 2014. Initially, the search for articles was based on the following four types of imaging modalities for evaluating BRONJ: computed tomography, plain film radiographs, magnetic resonance imaging, and nuclear bone scanning. Results. Eleven out of the 79 initially selected articles met the inclusion criteria. Most of the selected articles were cross-sectional studies. Regarding the selected studies, 54.5% have used plain films radiographs and 54.5% were based on computed tomography findings. All of the selected studies showed a small number of patients and none of the selected studies have tested the accuracy of the imaging examination for evaluating BRONJ. Conclusions. This critical review showed a scarcity of quantitative studies that analyzed the typical imaging findings related to BRONJ. Further studies are necessary in order to analyze the role of different imaging techniques in the assessment of BRONJ.
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publishDate 2014-01-01
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series International Journal of Dentistry
spelling doaj-art-a696a8c5998e44e39bbfbb9cd5b30f2a2025-02-03T01:10:44ZengWileyInternational Journal of Dentistry1687-87281687-87362014-01-01201410.1155/2014/784348784348Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative StudiesAndré Ferreira Leite0Fernanda dos Santos Ogata1Nilce Santos de Melo2Paulo Tadeu de Souza Figueiredo3Oral Radiology, Department of Dentistry, Faculty of Health Science, University of Brasília, Campus Universitario Darcy Ribeiro, Asa Norte, 70910-900 Brasília, DF, BrazilUniversity of Brasília, Campus Universitario Darcy Ribeiro, Asa Norte, 70910-900 Brasília, DF, BrazilOral Pathology, Department of Dentistry, Faculty of Health Science, University of Brasília, Campus Universitario Darcy Ribeiro, Asa Norte, 70910-900 Brasília, DF, BrazilOral Radiology, Department of Dentistry, Faculty of Health Science, University of Brasília, Campus Universitario Darcy Ribeiro, Asa Norte, 70910-900 Brasília, DF, BrazilObjectives. This paper offers a critical review of published information on the imaging strategies used for diagnosing bisphosphonate-associated osteonecrosis of the jaw (BRONJ) in patients taking intravenous bisphosphonates, pointing at the different methodologies and results of existing literature. Methods. Electronic literature search was performed in order to identify as many quantitative studies that discussed the imaging findings of BRONJ up to February 2014. Initially, the search for articles was based on the following four types of imaging modalities for evaluating BRONJ: computed tomography, plain film radiographs, magnetic resonance imaging, and nuclear bone scanning. Results. Eleven out of the 79 initially selected articles met the inclusion criteria. Most of the selected articles were cross-sectional studies. Regarding the selected studies, 54.5% have used plain films radiographs and 54.5% were based on computed tomography findings. All of the selected studies showed a small number of patients and none of the selected studies have tested the accuracy of the imaging examination for evaluating BRONJ. Conclusions. This critical review showed a scarcity of quantitative studies that analyzed the typical imaging findings related to BRONJ. Further studies are necessary in order to analyze the role of different imaging techniques in the assessment of BRONJ.http://dx.doi.org/10.1155/2014/784348
spellingShingle André Ferreira Leite
Fernanda dos Santos Ogata
Nilce Santos de Melo
Paulo Tadeu de Souza Figueiredo
Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies
International Journal of Dentistry
title Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies
title_full Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies
title_fullStr Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies
title_full_unstemmed Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies
title_short Imaging Findings of Bisphosphonate-Related Osteonecrosis of the Jaws: A Critical Review of the Quantitative Studies
title_sort imaging findings of bisphosphonate related osteonecrosis of the jaws a critical review of the quantitative studies
url http://dx.doi.org/10.1155/2014/784348
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