Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

ObjectivePapillary thyroid carcinoma (PTC) has a high recurrence rate and lacks reliable diagnostic biomarkers. This study aims to identify robust transcriptomic biomarkers for PTC diagnosis through integrative bioinformatics approaches and elucidate the cellular mechanisms underlying PTC pathogenes...

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Bibliographic Details
Main Authors:	Wanchen Cao, Kai Gao, Yi Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Genetics
Subjects:	papillary thyroid carcinoma weighted gene co-expression network analysis gene set enrichment analysis machine learning ScRNA-seq
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1536198/full
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