Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia
Pulmonary infections are the most common clinical manifestations of Nocardia species. There is an increase in cases of nocardial infections occurring worldwide attributable to the increase in the immunosuppressed population. The availability of molecular methods has aided the detection of more numbe...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2019/5184386 |
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| _version_ | 1850169165520830464 |
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| author | Harish Manoharan Sribal Selvarajan K. S. Sridharan Uma Sekar |
| author_facet | Harish Manoharan Sribal Selvarajan K. S. Sridharan Uma Sekar |
| author_sort | Harish Manoharan |
| collection | DOAJ |
| description | Pulmonary infections are the most common clinical manifestations of Nocardia species. There is an increase in cases of nocardial infections occurring worldwide attributable to the increase in the immunosuppressed population. The availability of molecular methods has aided the detection of more number of cases as well as unusual species. Still, it remains one of the most underdiagnosed pathogens. Recognition of drug resistance in this organism has now mandated early and precise identification with speciation for effective treatment and management. Nocardial species identity can predict antimicrobial susceptibility and guide clinical management. Here, we report two cases of pulmonary nocardiosis caused by unusual species of Nocardia, namely, N. cyriacigeorgica and N. beijingensis identified by 16S rRNA gene-based sequencing. These cases are being reported for their rarity. |
| format | Article |
| id | doaj-art-a68ac1e95ff84940954dbe9f35d09d7f |
| institution | OA Journals |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-a68ac1e95ff84940954dbe9f35d09d7f2025-08-20T02:20:48ZengWileyCase Reports in Infectious Diseases2090-66252090-66332019-01-01201910.1155/2019/51843865184386Pulmonary Infections Caused by Emerging Pathogenic Species of NocardiaHarish Manoharan0Sribal Selvarajan1K. S. Sridharan2Uma Sekar3Sri Ramachandra Institute of Higher Education and Research, Chennai, IndiaSri Ramachandra Institute of Higher Education and Research, Chennai, IndiaSri Ramachandra Institute of Higher Education and Research, Chennai, IndiaSri Ramachandra Institute of Higher Education and Research, Chennai, IndiaPulmonary infections are the most common clinical manifestations of Nocardia species. There is an increase in cases of nocardial infections occurring worldwide attributable to the increase in the immunosuppressed population. The availability of molecular methods has aided the detection of more number of cases as well as unusual species. Still, it remains one of the most underdiagnosed pathogens. Recognition of drug resistance in this organism has now mandated early and precise identification with speciation for effective treatment and management. Nocardial species identity can predict antimicrobial susceptibility and guide clinical management. Here, we report two cases of pulmonary nocardiosis caused by unusual species of Nocardia, namely, N. cyriacigeorgica and N. beijingensis identified by 16S rRNA gene-based sequencing. These cases are being reported for their rarity.http://dx.doi.org/10.1155/2019/5184386 |
| spellingShingle | Harish Manoharan Sribal Selvarajan K. S. Sridharan Uma Sekar Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia Case Reports in Infectious Diseases |
| title | Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia |
| title_full | Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia |
| title_fullStr | Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia |
| title_full_unstemmed | Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia |
| title_short | Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia |
| title_sort | pulmonary infections caused by emerging pathogenic species of nocardia |
| url | http://dx.doi.org/10.1155/2019/5184386 |
| work_keys_str_mv | AT harishmanoharan pulmonaryinfectionscausedbyemergingpathogenicspeciesofnocardia AT sribalselvarajan pulmonaryinfectionscausedbyemergingpathogenicspeciesofnocardia AT kssridharan pulmonaryinfectionscausedbyemergingpathogenicspeciesofnocardia AT umasekar pulmonaryinfectionscausedbyemergingpathogenicspeciesofnocardia |