A Review of Therapies for <i>Clostridioides difficile</i> Infection

<i>Clostridioides difficile</i> is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of <i>Clostridioides difficile</i> infection (CDI), it remains a leading cause...

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Main Authors: Faiza Morado, Neha Nanda
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/14/1/17
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author Faiza Morado
Neha Nanda
author_facet Faiza Morado
Neha Nanda
author_sort Faiza Morado
collection DOAJ
description <i>Clostridioides difficile</i> is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of <i>Clostridioides difficile</i> infection (CDI), it remains a leading cause of healthcare-associated infections. CDI is associated with significant clinical, social, and economic burdens. Therefore, it is imperative to provide optimal and timely therapy for CDI. We conducted a systematic literature review and offer treatment recommendations based on available evidence for the treatment and prevention of CDI.
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institution Kabale University
issn 2079-6382
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series Antibiotics
spelling doaj-art-a67c7576b81243c6864a65c5985b8b512025-01-24T13:18:33ZengMDPI AGAntibiotics2079-63822024-12-011411710.3390/antibiotics14010017A Review of Therapies for <i>Clostridioides difficile</i> InfectionFaiza Morado0Neha Nanda1Department of Pharmacy, Keck Medical Center, University of Southern California, Los Angeles, CA 90033, USADivision of Infectious Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA<i>Clostridioides difficile</i> is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of <i>Clostridioides difficile</i> infection (CDI), it remains a leading cause of healthcare-associated infections. CDI is associated with significant clinical, social, and economic burdens. Therefore, it is imperative to provide optimal and timely therapy for CDI. We conducted a systematic literature review and offer treatment recommendations based on available evidence for the treatment and prevention of CDI.https://www.mdpi.com/2079-6382/14/1/17<i>C. difficile</i> infectionrecurrent <i>C. difficile</i> infectionmetronidazolevacomycinfidaxomicinfecal microbiota transplantation
spellingShingle Faiza Morado
Neha Nanda
A Review of Therapies for <i>Clostridioides difficile</i> Infection
Antibiotics
<i>C. difficile</i> infection
recurrent <i>C. difficile</i> infection
metronidazole
vacomycin
fidaxomicin
fecal microbiota transplantation
title A Review of Therapies for <i>Clostridioides difficile</i> Infection
title_full A Review of Therapies for <i>Clostridioides difficile</i> Infection
title_fullStr A Review of Therapies for <i>Clostridioides difficile</i> Infection
title_full_unstemmed A Review of Therapies for <i>Clostridioides difficile</i> Infection
title_short A Review of Therapies for <i>Clostridioides difficile</i> Infection
title_sort review of therapies for i clostridioides difficile i infection
topic <i>C. difficile</i> infection
recurrent <i>C. difficile</i> infection
metronidazole
vacomycin
fidaxomicin
fecal microbiota transplantation
url https://www.mdpi.com/2079-6382/14/1/17
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