Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients
Aim. Study was designed to assess relationship between aortic compliance and homogeneity of heart electrical activity in dialysis patients. Methods. Study group was consisted of 120 dialyzed patients; 57 (age 50,7±7,1) were on continuous ambulatory peritoneal dialysis (CAPD) and 73 (age 51,6±7,6) w...
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2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/947907 |
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| author | Tomasz Zapolski Andrzej Jaroszyński Anna Drelich-Zbroja Anna Wysocka Jacek Furmaga Andrzej Wysokiński Andrzej Książek Małgorzata Szczerbo-Trojanowska Sławomir Rudzki |
| author_facet | Tomasz Zapolski Andrzej Jaroszyński Anna Drelich-Zbroja Anna Wysocka Jacek Furmaga Andrzej Wysokiński Andrzej Książek Małgorzata Szczerbo-Trojanowska Sławomir Rudzki |
| author_sort | Tomasz Zapolski |
| collection | DOAJ |
| description | Aim. Study was designed to assess relationship between aortic compliance and homogeneity of heart electrical activity in dialysis patients. Methods. Study group was consisted of 120 dialyzed patients; 57 (age 50,7±7,1) were on continuous ambulatory peritoneal dialysis (CAPD) and 73 (age 51,6±7,6) were hemodialyzed (HD). Three-dimensional vectorocardiographic (VCG) monitoring was done to assess: QRS-𝑇angle, 𝑇el and 𝑇az. Echocardiography was performed to assess: Aomax, Aomin, ASI (aortic siffness index). Results. ASI in HD as well as in CAPD patients was significantly higher compared to controls [resp., 5,51 (±1,32), 5,83 (±1,41), 3,07 (±1,09)]. Cut-off value of ASI was 5,67. In HD patients strong correlations between ASI and QRS-𝑇angle, 𝑇el and 𝑇az were determined (resp., 𝑟=0,429, 𝑃<0,001; 𝑟=0,432, 𝑃≤0,001 and 𝑟=0,387, 𝑃=0,001). In CAPD group were significant association between ASI and QRS-𝑇angle, 𝑇el and 𝑇az (resp., 𝑟=0,452, 𝑃<0,001; 𝑟=0,417, 𝑃<0,001 and 𝑟=0,390, 𝑃=0,001). ASI was independently and markedly associated with: QRS-𝑇angle, 𝑇elev, 𝑇az, ADMA, cTnT, CRP, Total-chol, LDL-chol in HD and CAPD patients. Conclusions. ASI and VCG indices are higher in HD and CAPD patients. Correlation between ASI and VCG parameters may reflect unfavourable influence of poor aortic compliance on the electrical activity of the heart in dialyzed patients. Hypertrophy aggravates repolarization disturbances in hemodialyzed patients. |
| format | Article |
| id | doaj-art-a66e2113c04d4404b2e98394a909a1c7 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
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| series | The Scientific World Journal |
| spelling | doaj-art-a66e2113c04d4404b2e98394a909a1c72025-02-03T01:20:40ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/947907947907Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed PatientsTomasz Zapolski0Andrzej Jaroszyński1Anna Drelich-Zbroja2Anna Wysocka3Jacek Furmaga4Andrzej Wysokiński5Andrzej Książek6Małgorzata Szczerbo-Trojanowska7Sławomir Rudzki8Chair and Department of Cardiology, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandChair and Department of Family Medicine, Medical University of Lublin, ul. Staszica 11, 20–081 Lublin, PolandDepartment of Interventional Radiology and Neuroradiology, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandChair and Department of Cardiology, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandFirst Chair and Department of General and Transplant Surgery, and Clinical Nutrition, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandChair and Department of Cardiology, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandChair and Department of Nephrology, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandDepartment of Interventional Radiology and Neuroradiology, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandFirst Chair and Department of General and Transplant Surgery, and Clinical Nutrition, Medical University of Lublin, ul. Jaczewskiego 8, 20–954 Lublin, PolandAim. Study was designed to assess relationship between aortic compliance and homogeneity of heart electrical activity in dialysis patients. Methods. Study group was consisted of 120 dialyzed patients; 57 (age 50,7±7,1) were on continuous ambulatory peritoneal dialysis (CAPD) and 73 (age 51,6±7,6) were hemodialyzed (HD). Three-dimensional vectorocardiographic (VCG) monitoring was done to assess: QRS-𝑇angle, 𝑇el and 𝑇az. Echocardiography was performed to assess: Aomax, Aomin, ASI (aortic siffness index). Results. ASI in HD as well as in CAPD patients was significantly higher compared to controls [resp., 5,51 (±1,32), 5,83 (±1,41), 3,07 (±1,09)]. Cut-off value of ASI was 5,67. In HD patients strong correlations between ASI and QRS-𝑇angle, 𝑇el and 𝑇az were determined (resp., 𝑟=0,429, 𝑃<0,001; 𝑟=0,432, 𝑃≤0,001 and 𝑟=0,387, 𝑃=0,001). In CAPD group were significant association between ASI and QRS-𝑇angle, 𝑇el and 𝑇az (resp., 𝑟=0,452, 𝑃<0,001; 𝑟=0,417, 𝑃<0,001 and 𝑟=0,390, 𝑃=0,001). ASI was independently and markedly associated with: QRS-𝑇angle, 𝑇elev, 𝑇az, ADMA, cTnT, CRP, Total-chol, LDL-chol in HD and CAPD patients. Conclusions. ASI and VCG indices are higher in HD and CAPD patients. Correlation between ASI and VCG parameters may reflect unfavourable influence of poor aortic compliance on the electrical activity of the heart in dialyzed patients. Hypertrophy aggravates repolarization disturbances in hemodialyzed patients.http://dx.doi.org/10.1100/2012/947907 |
| spellingShingle | Tomasz Zapolski Andrzej Jaroszyński Anna Drelich-Zbroja Anna Wysocka Jacek Furmaga Andrzej Wysokiński Andrzej Książek Małgorzata Szczerbo-Trojanowska Sławomir Rudzki Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients The Scientific World Journal |
| title | Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients |
| title_full | Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients |
| title_fullStr | Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients |
| title_full_unstemmed | Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients |
| title_short | Aortic Stiffness, Left Ventricle Hypertrophy, and Homogeneity of Ventricle Repolarization in Adult Dialyzed Patients |
| title_sort | aortic stiffness left ventricle hypertrophy and homogeneity of ventricle repolarization in adult dialyzed patients |
| url | http://dx.doi.org/10.1100/2012/947907 |
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