Nucleosome dynamics render heterochromatin accessible in living human cells

Abstract The eukaryotic genome is packaged into chromatin, which is composed of a nucleosomal filament that coils up to form more compact structures. Chromatin exists in two main forms: euchromatin, which is relatively decondensed and enriched in transcriptionally active genes, and heterochromatin,...

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Bibliographic Details
Main Authors: Hemant K. Prajapati, Zhuwei Xu, Peter R. Eriksson, David J. Clark
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59994-7
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