Hybridisation of in silico and in vitro bioassays for studying the activation of Nrf2 by natural compounds

Abstract Oxidative stress, characterized by the damaging accumulation of free radicals, is associated with various diseases, including cardiovascular, neurodegenerative, and metabolic disorders. The transcription factor Nrf2 is pivotal in cellular defense against oxidative stress by regulating genes...

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Bibliographic Details
Main Authors: Bui Quoc Huy Nguyen, Nguyen Thien Han Le, Thi Yen Nhi Nguyen, Hoang Khue Tu Nguyen, Chia-Hung Yen, Minh Hien Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-82559-5
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