Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report

Abstract Herpes zoster Ophthalmicus (HZO) affecting the ophthalmic division (V1) of the trigeminal nerve. HZO may cause extraocular muscle palsies, with the third nerve being the most commonly affected and the fourth nerve the least. The combined involvement of the optic nerve and isolated paralysis...

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Main Authors: Farshad Afshar, Mohammad Sadegh Khalilian, Mohsen Pourazizi, Mohammad Amin Najafi
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-025-03870-x
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author Farshad Afshar
Mohammad Sadegh Khalilian
Mohsen Pourazizi
Mohammad Amin Najafi
author_facet Farshad Afshar
Mohammad Sadegh Khalilian
Mohsen Pourazizi
Mohammad Amin Najafi
author_sort Farshad Afshar
collection DOAJ
description Abstract Herpes zoster Ophthalmicus (HZO) affecting the ophthalmic division (V1) of the trigeminal nerve. HZO may cause extraocular muscle palsies, with the third nerve being the most commonly affected and the fourth nerve the least. The combined involvement of the optic nerve and isolated paralysis of the eye muscle is very rare, with only limited case reports documenting this complication of ocular herpes zoster. This case report also describes a case of optic nerve involvement with 6th nerve palsy, which was treated with corticosteroid and valacyclovir.
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institution Kabale University
issn 1471-2415
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publishDate 2025-01-01
publisher BMC
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series BMC Ophthalmology
spelling doaj-art-a635799c8d474e548cecaeab339bad3a2025-01-19T12:14:28ZengBMCBMC Ophthalmology1471-24152025-01-012511510.1186/s12886-025-03870-xHerpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case reportFarshad Afshar0Mohammad Sadegh Khalilian1Mohsen Pourazizi2Mohammad Amin Najafi3Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical SciencesIsfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical SciencesIsfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical SciencesIsfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical SciencesAbstract Herpes zoster Ophthalmicus (HZO) affecting the ophthalmic division (V1) of the trigeminal nerve. HZO may cause extraocular muscle palsies, with the third nerve being the most commonly affected and the fourth nerve the least. The combined involvement of the optic nerve and isolated paralysis of the eye muscle is very rare, with only limited case reports documenting this complication of ocular herpes zoster. This case report also describes a case of optic nerve involvement with 6th nerve palsy, which was treated with corticosteroid and valacyclovir.https://doi.org/10.1186/s12886-025-03870-xAbducens nerve palsySixth cranial nerve palsyOphthalmoplegiaHerpes zoster Ophthalmicus (HZO)Herpes zosterAcute retrobulbar optic neuritis (ON)
spellingShingle Farshad Afshar
Mohammad Sadegh Khalilian
Mohsen Pourazizi
Mohammad Amin Najafi
Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report
BMC Ophthalmology
Abducens nerve palsy
Sixth cranial nerve palsy
Ophthalmoplegia
Herpes zoster Ophthalmicus (HZO)
Herpes zoster
Acute retrobulbar optic neuritis (ON)
title Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report
title_full Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report
title_fullStr Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report
title_full_unstemmed Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report
title_short Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report
title_sort herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy a case report
topic Abducens nerve palsy
Sixth cranial nerve palsy
Ophthalmoplegia
Herpes zoster Ophthalmicus (HZO)
Herpes zoster
Acute retrobulbar optic neuritis (ON)
url https://doi.org/10.1186/s12886-025-03870-x
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AT mohsenpourazizi herpeszosterophthalmicuswithacuteretrobulbaropticneuritisandabducensnervepalsyacasereport
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