Current Concepts in the Biopsy of Musculoskeletal Tumors

In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis...

Full description

Saved in:
Bibliographic Details
Main Authors: Costantino Errani, Francesco Traina, Fabrizio Perna, Carlotta Calamelli, Cesare Faldini
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/538152
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832548342324789248
author Costantino Errani
Francesco Traina
Fabrizio Perna
Carlotta Calamelli
Cesare Faldini
author_facet Costantino Errani
Francesco Traina
Fabrizio Perna
Carlotta Calamelli
Cesare Faldini
author_sort Costantino Errani
collection DOAJ
description In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important and complex surgery in the staging process. It must be done carefully, so as not to adversely affect the outcome. Technical considerations include proper location and orientation of the biopsy incision and meticulous hemostasis. It is necessary to obtain tissue for a histological diagnosis without spreading the tumor and so compromise the treatment. Furthermore, the surgeon does not open compartmental barriers, anatomic planes, joint space, and tissue area around neurovascular bundles. Nevertheless, avoid producing a hematoma. Biopsy should be carefully planned according to the site and definitive surgery and should be performed by an orthopedic surgeon with an experience in musculoskeletal oncology who will perform the definitive surgery. Improperly done, it can complicate patient care and sometimes even eliminate treatment options. Different biopsy techniques are suitable: fine-needle aspiration, core-needle biopsy, and incisional biopsy. The choice of biopsy depends on the size, the location of the lesion, and the experience of the pathologist.
format Article
id doaj-art-a63069141e66499f98a54177588e8966
institution Kabale University
issn 1537-744X
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-a63069141e66499f98a54177588e89662025-02-03T06:14:19ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/538152538152Current Concepts in the Biopsy of Musculoskeletal TumorsCostantino Errani0Francesco Traina1Fabrizio Perna2Carlotta Calamelli3Cesare Faldini4Orthopaedic Service, Rizzoli Institute, Rizzoli-Sicilia, Strada Statale 113 Km, 246-90011 Bagheria, ItalyOrthopaedic Service, Rizzoli Institute, Rizzoli-Sicilia, Strada Statale 113 Km, 246-90011 Bagheria, ItalyOrthopaedic Service, Rizzoli Institute, Rizzoli-Sicilia, Strada Statale 113 Km, 246-90011 Bagheria, ItalyOrthopaedic Service, Rizzoli Institute, Rizzoli-Sicilia, Strada Statale 113 Km, 246-90011 Bagheria, ItalyOrthopaedic Service, Rizzoli Institute, Rizzoli-Sicilia, Strada Statale 113 Km, 246-90011 Bagheria, ItalyIn the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important and complex surgery in the staging process. It must be done carefully, so as not to adversely affect the outcome. Technical considerations include proper location and orientation of the biopsy incision and meticulous hemostasis. It is necessary to obtain tissue for a histological diagnosis without spreading the tumor and so compromise the treatment. Furthermore, the surgeon does not open compartmental barriers, anatomic planes, joint space, and tissue area around neurovascular bundles. Nevertheless, avoid producing a hematoma. Biopsy should be carefully planned according to the site and definitive surgery and should be performed by an orthopedic surgeon with an experience in musculoskeletal oncology who will perform the definitive surgery. Improperly done, it can complicate patient care and sometimes even eliminate treatment options. Different biopsy techniques are suitable: fine-needle aspiration, core-needle biopsy, and incisional biopsy. The choice of biopsy depends on the size, the location of the lesion, and the experience of the pathologist.http://dx.doi.org/10.1155/2013/538152
spellingShingle Costantino Errani
Francesco Traina
Fabrizio Perna
Carlotta Calamelli
Cesare Faldini
Current Concepts in the Biopsy of Musculoskeletal Tumors
The Scientific World Journal
title Current Concepts in the Biopsy of Musculoskeletal Tumors
title_full Current Concepts in the Biopsy of Musculoskeletal Tumors
title_fullStr Current Concepts in the Biopsy of Musculoskeletal Tumors
title_full_unstemmed Current Concepts in the Biopsy of Musculoskeletal Tumors
title_short Current Concepts in the Biopsy of Musculoskeletal Tumors
title_sort current concepts in the biopsy of musculoskeletal tumors
url http://dx.doi.org/10.1155/2013/538152
work_keys_str_mv AT costantinoerrani currentconceptsinthebiopsyofmusculoskeletaltumors
AT francescotraina currentconceptsinthebiopsyofmusculoskeletaltumors
AT fabrizioperna currentconceptsinthebiopsyofmusculoskeletaltumors
AT carlottacalamelli currentconceptsinthebiopsyofmusculoskeletaltumors
AT cesarefaldini currentconceptsinthebiopsyofmusculoskeletaltumors