Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
Aim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the form...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2019-08-01
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| Series: | Acta Biomedica Scientifica |
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| Online Access: | https://www.actabiomedica.ru/jour/article/view/2132 |
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| author | A. A. Shchuko S. I. Kolesnikov T. N. Iurevа A. N. Zlobina |
| author_facet | A. A. Shchuko S. I. Kolesnikov T. N. Iurevа A. N. Zlobina |
| author_sort | A. A. Shchuko |
| collection | DOAJ |
| description | Aim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the formation of acute and chronic forms of the disease. Material and methods. 40 people with central serous chorioretinopathy and 26 control subjects were examined with the assessment of psychophysiological (psychoemotional) and hormonal changes.Results. The most informative criteria have been identified which determine various forms of the clinical course of central serous chorioretinopathy: the area of damage to the retinal pigment epithelium, psycho-emotional changes (the difficulties of role-playing, dependence on other people in domestic and professional environment, a high degree of reactive and personal anxiety, paranoia and level of distress), violation of the psycho-physiological characteristics of the state of the visual system, changes in hormonal regulation (cortisol, thyroid hormones, dehydroepiandrosterone, melatonin, 17-OH-progesterone, testosterone).Conclusion. The complex of psychophysiological changes that form the basis for the pathogenesis of central serous chorioretinopathy, according to the feedback mechanism, enhances the initial moments of the disease, exacerbates the severity of clinical manifestations and leads to chronicity of the pathological process, causing, thus, the complexity of diagnosis and treatment of central serous chorioretinopathy. |
| format | Article |
| id | doaj-art-a6127d241608426f9d0f05f7aa3dcd39 |
| institution | Kabale University |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| publishDate | 2019-08-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj-art-a6127d241608426f9d0f05f7aa3dcd392025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962019-08-014411912310.29413/ABS.2019-4.4.181913Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous ChorioretinopathyA. A. Shchuko0S. I. Kolesnikov1T. N. Iurevа2A. N. Zlobina3Irkutsk Branch of S. Fyodorov Eye Microsurgery Federal State InstitutionScientific Сentre for Family Health and Human Reproduction ProblemsIrkutsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution; Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuing Professional EducationIrkutsk Branch of S. Fyodorov Eye Microsurgery Federal State InstitutionAim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the formation of acute and chronic forms of the disease. Material and methods. 40 people with central serous chorioretinopathy and 26 control subjects were examined with the assessment of psychophysiological (psychoemotional) and hormonal changes.Results. The most informative criteria have been identified which determine various forms of the clinical course of central serous chorioretinopathy: the area of damage to the retinal pigment epithelium, psycho-emotional changes (the difficulties of role-playing, dependence on other people in domestic and professional environment, a high degree of reactive and personal anxiety, paranoia and level of distress), violation of the psycho-physiological characteristics of the state of the visual system, changes in hormonal regulation (cortisol, thyroid hormones, dehydroepiandrosterone, melatonin, 17-OH-progesterone, testosterone).Conclusion. The complex of psychophysiological changes that form the basis for the pathogenesis of central serous chorioretinopathy, according to the feedback mechanism, enhances the initial moments of the disease, exacerbates the severity of clinical manifestations and leads to chronicity of the pathological process, causing, thus, the complexity of diagnosis and treatment of central serous chorioretinopathy.https://www.actabiomedica.ru/jour/article/view/2132central serous chorioretinopathyvisual systempsycho-physiological reactionsendocrine changespsychoemotional changesdisease pathogenesis |
| spellingShingle | A. A. Shchuko S. I. Kolesnikov T. N. Iurevа A. N. Zlobina Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy Acta Biomedica Scientifica central serous chorioretinopathy visual system psycho-physiological reactions endocrine changes psychoemotional changes disease pathogenesis |
| title | Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy |
| title_full | Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy |
| title_fullStr | Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy |
| title_full_unstemmed | Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy |
| title_short | Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy |
| title_sort | evaluation of psychophysiological and hormonal changes in acute and chronic forms of central serous chorioretinopathy |
| topic | central serous chorioretinopathy visual system psycho-physiological reactions endocrine changes psychoemotional changes disease pathogenesis |
| url | https://www.actabiomedica.ru/jour/article/view/2132 |
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