First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease

We report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for...

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Main Authors: Paul Baciu, Christopher Yang, Aldo Fantin, Deborah Darnley-Fisch, Uday Desai
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2014/782923
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author Paul Baciu
Christopher Yang
Aldo Fantin
Deborah Darnley-Fisch
Uday Desai
author_facet Paul Baciu
Christopher Yang
Aldo Fantin
Deborah Darnley-Fisch
Uday Desai
author_sort Paul Baciu
collection DOAJ
description We report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for routine examination and was found to have sea-fan peripheral neovascularization bilaterally without maculopathy. Hemoglobin analysis revealed Hb SE heterozygosity. Sector laser photocoagulation to areas of nonperfusion in both eyes resulted in regression of the peripheral neovascularization over a period of 6 months. Although Hb SE disease is rare, the incidence of Hb SE disease is postulated to rise in the future. Awareness of its potential ocular complications is needed to appropriately refer these patients for screening.
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institution Kabale University
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language English
publishDate 2014-01-01
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-a610f1a356dc416cba5a7f0c6842bf0e2025-02-03T05:49:44ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302014-01-01201410.1155/2014/782923782923First Reported Case of Proliferative Retinopathy in Hemoglobin SE DiseasePaul Baciu0Christopher Yang1Aldo Fantin2Deborah Darnley-Fisch3Uday Desai4Department of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USAWe report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for routine examination and was found to have sea-fan peripheral neovascularization bilaterally without maculopathy. Hemoglobin analysis revealed Hb SE heterozygosity. Sector laser photocoagulation to areas of nonperfusion in both eyes resulted in regression of the peripheral neovascularization over a period of 6 months. Although Hb SE disease is rare, the incidence of Hb SE disease is postulated to rise in the future. Awareness of its potential ocular complications is needed to appropriately refer these patients for screening.http://dx.doi.org/10.1155/2014/782923
spellingShingle Paul Baciu
Christopher Yang
Aldo Fantin
Deborah Darnley-Fisch
Uday Desai
First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
Case Reports in Ophthalmological Medicine
title First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
title_full First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
title_fullStr First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
title_full_unstemmed First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
title_short First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
title_sort first reported case of proliferative retinopathy in hemoglobin se disease
url http://dx.doi.org/10.1155/2014/782923
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AT aldofantin firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease
AT deborahdarnleyfisch firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease
AT udaydesai firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease