First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease
We report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for...
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Wiley
2014-01-01
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Series: | Case Reports in Ophthalmological Medicine |
Online Access: | http://dx.doi.org/10.1155/2014/782923 |
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author | Paul Baciu Christopher Yang Aldo Fantin Deborah Darnley-Fisch Uday Desai |
author_facet | Paul Baciu Christopher Yang Aldo Fantin Deborah Darnley-Fisch Uday Desai |
author_sort | Paul Baciu |
collection | DOAJ |
description | We report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for routine examination and was found to have sea-fan peripheral neovascularization bilaterally without maculopathy. Hemoglobin analysis revealed Hb SE heterozygosity. Sector laser photocoagulation to areas of nonperfusion in both eyes resulted in regression of the peripheral neovascularization over a period of 6 months. Although Hb SE disease is rare, the incidence of Hb SE disease is postulated to rise in the future. Awareness of its potential ocular complications is needed to appropriately refer these patients for screening. |
format | Article |
id | doaj-art-a610f1a356dc416cba5a7f0c6842bf0e |
institution | Kabale University |
issn | 2090-6722 2090-6730 |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Ophthalmological Medicine |
spelling | doaj-art-a610f1a356dc416cba5a7f0c6842bf0e2025-02-03T05:49:44ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302014-01-01201410.1155/2014/782923782923First Reported Case of Proliferative Retinopathy in Hemoglobin SE DiseasePaul Baciu0Christopher Yang1Aldo Fantin2Deborah Darnley-Fisch3Uday Desai4Department of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Ophthalmology, Henry Ford Hospital, 2799 W. Grand Boulevard, Detroit, MI 48202, USAWe report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for routine examination and was found to have sea-fan peripheral neovascularization bilaterally without maculopathy. Hemoglobin analysis revealed Hb SE heterozygosity. Sector laser photocoagulation to areas of nonperfusion in both eyes resulted in regression of the peripheral neovascularization over a period of 6 months. Although Hb SE disease is rare, the incidence of Hb SE disease is postulated to rise in the future. Awareness of its potential ocular complications is needed to appropriately refer these patients for screening.http://dx.doi.org/10.1155/2014/782923 |
spellingShingle | Paul Baciu Christopher Yang Aldo Fantin Deborah Darnley-Fisch Uday Desai First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease Case Reports in Ophthalmological Medicine |
title | First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease |
title_full | First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease |
title_fullStr | First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease |
title_full_unstemmed | First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease |
title_short | First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease |
title_sort | first reported case of proliferative retinopathy in hemoglobin se disease |
url | http://dx.doi.org/10.1155/2014/782923 |
work_keys_str_mv | AT paulbaciu firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease AT christopheryang firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease AT aldofantin firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease AT deborahdarnleyfisch firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease AT udaydesai firstreportedcaseofproliferativeretinopathyinhemoglobinsedisease |