Identification of lncRNAs in peripheral blood mononuclear cells associated with sepsis immunosuppression based on weighted gene co-expression network analysis

Identification of lncRNAs in peripheral blood mononuclear cells associated with sepsis immunosuppression based on weighted gene co-expression network analysis

Abstract Background Sepsis-induced immunosuppression involves complex molecular mechanisms, including dysregulated long noncoding RNAs (lncRNAs), which remain poorly understood. Objective We aimed to identify immunosuppression-related lncRNAs and their functional pathways in sepsis. Methods: Using w...

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Bibliographic Details
Main Authors: Wenjia Zhang, Yan Li, Gang Li, Aijia Zhang, Wende Sun
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Hereditas
Subjects:
Sepsis
Immunosuppression
lncRNAs
WGCNA
Hub genes
Online Access:https://doi.org/10.1186/s41065-025-00400-z
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