Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review

Carcinoma of the gallbladder is the most common biliary tract cancer. The majority of gallbladder cancers are adenocarcinomas, whereas clear-cell carcinoma of the gallbladder (CCG) is a rarely recorded variant. Usually, diagnosis is established incidentally after cholecystectomy, performed for anoth...

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Main Authors: Panayiotis Papatheodorou, Kyriakos Frantzeskou, Kyriaki Konstantinou, Elena Theophanous
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2023/8104679
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author Panayiotis Papatheodorou
Kyriakos Frantzeskou
Kyriaki Konstantinou
Elena Theophanous
author_facet Panayiotis Papatheodorou
Kyriakos Frantzeskou
Kyriaki Konstantinou
Elena Theophanous
author_sort Panayiotis Papatheodorou
collection DOAJ
description Carcinoma of the gallbladder is the most common biliary tract cancer. The majority of gallbladder cancers are adenocarcinomas, whereas clear-cell carcinoma of the gallbladder (CCG) is a rarely recorded variant. Usually, diagnosis is established incidentally after cholecystectomy, performed for another reason. Clinically, the different histological types of carcinomas are impossible to be recognized preoperatively, since they present with a wide and common range of symptoms. We present a male patient who underwent an emergency cholecystectomy due to suspected perforation. After an uneventful postoperative period, the histopathological report led to the diagnosis of CCG, but the surgical margins were infiltrated by the tumor. The patient decided not to proceed with any additional treatment and passed away 8 months after the operation. In conclusion, it is of great necessity to record such unusual cases and enriches global knowledge with information clinically and educationally noteworthy.
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spelling doaj-art-a602cf0508e24bb7b2f12d209fceadb42025-08-20T02:20:48ZengWileyCase Reports in Surgery2090-69192023-01-01202310.1155/2023/8104679Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature ReviewPanayiotis Papatheodorou0Kyriakos Frantzeskou1Kyriaki Konstantinou2Elena Theophanous3General Surgery DepartmentGeneral Surgery DepartmentGeneral Surgery DepartmentHistopathology DepartmentCarcinoma of the gallbladder is the most common biliary tract cancer. The majority of gallbladder cancers are adenocarcinomas, whereas clear-cell carcinoma of the gallbladder (CCG) is a rarely recorded variant. Usually, diagnosis is established incidentally after cholecystectomy, performed for another reason. Clinically, the different histological types of carcinomas are impossible to be recognized preoperatively, since they present with a wide and common range of symptoms. We present a male patient who underwent an emergency cholecystectomy due to suspected perforation. After an uneventful postoperative period, the histopathological report led to the diagnosis of CCG, but the surgical margins were infiltrated by the tumor. The patient decided not to proceed with any additional treatment and passed away 8 months after the operation. In conclusion, it is of great necessity to record such unusual cases and enriches global knowledge with information clinically and educationally noteworthy.http://dx.doi.org/10.1155/2023/8104679
spellingShingle Panayiotis Papatheodorou
Kyriakos Frantzeskou
Kyriaki Konstantinou
Elena Theophanous
Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
Case Reports in Surgery
title Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
title_full Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
title_fullStr Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
title_full_unstemmed Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
title_short Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
title_sort gallbladder clear cell carcinoma report of a rare case and literature review
url http://dx.doi.org/10.1155/2023/8104679
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