SNRPB2 facilitates esophageal squamous cell carcinoma oncogenesis and progression via E2F4 stabilization

IntroductionEsophageal cancer (ESCA) is a highly aggressive malignancy with poor prognosis. Small nuclear ribonucleoprotein polypeptide B2 (SNRPB2) is a core component of the spliceosome involved in pre-mRNA splicing. However, its role in tumor development and progression remains largely unclear. Th...

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Main Authors: Feng Xu, Chen-Cheng Zhu, Chen Lu, Guang-Yao Ning, Ren-Quan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1610721/full
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