A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria
In the absence of specific antisera and molecular typing technique, selection of P antigen-negative red cell unit is a challenge. This article explains a new technique that can be used in emergency situations to screen P antigen-negative red cell unit for the transfusion of patients with paroxysmal...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-01-01
|
| Series: | Asian Journal of Transfusion Science |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ajts.AJTS_65_19 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | In the absence of specific antisera and molecular typing technique, selection of P antigen-negative red cell unit is a challenge. This article explains a new technique that can be used in emergency situations to screen P antigen-negative red cell unit for the transfusion of patients with paroxysmal cold hemoglobinuria tested positive for Donath-Landsteiner antibody. The technique is based on the theory behind the Donath-Landsteiner test, and it can be performed even in a transfusion laboratory with minimum facilities. |
|---|---|
| ISSN: | 0973-6247 1998-3565 |