Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial
Background: Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation. The purpose of this study was to evaluate the effectiveness of the use of penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving ex...
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Elsevier
2025-03-01
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| Series: | Integrative Medicine Research |
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| author | Ying He Gui-yuan Li Chun-zhi Tang Li-ming Lu Guang-yi Xiong Yi Gao Juan Tong Guang-en Zhong |
| author_facet | Ying He Gui-yuan Li Chun-zhi Tang Li-ming Lu Guang-yi Xiong Yi Gao Juan Tong Guang-en Zhong |
| author_sort | Ying He |
| collection | DOAJ |
| description | Background: Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation. The purpose of this study was to evaluate the effectiveness of the use of penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance among COPD patients. Methods: A total of 85 patients were recruited and randomly assigned to receive treatment with either penetrating needles with electrical stimulation (PE) or non-penetrating needles with electrical stimulation (NPE) 3 times a week for 8 weeks, thereby resulting in a total of 24 treatments. Both groups underwent exercise training. The evaluations were conducted at baseline, after 14 treatments, and after 24 treatments. Results: The PE group showed significant improvement in the 6-minute walk distance (6MWD) after the 14th treatment. For the pulmonary function test, percentage of maximal voluntary ventilation (MVV%), maximal expiratory flow (MEF) after 75% of the forced vital capacity (FVC), MEF after 50% of FVC, and MEF after 25% of FVC were improved in the PE group, and especially MVV% was significantly greater than that in the NPE group. For cardiopulmonary exercise testing, percentage of oxygen consumption per kg body weight (VO2/kg), percentage of ventilation volume per minute (VE), maximal ventilation volume per minute (VEmax), ventilatory equivalent for oxygen (VE/VO2), and ventilatory equivalent for carbon dioxide (VE/VCO2) were significantly higher than the NPE group. The scores of COPD assessment test in the PE group significantly improved. Conclusion: Treatment with penetrating needles with electrical stimulation combined with exercise training may be clinically useful for COPD patients in relieving dyspnea and improving exercise tolerance. Trial Registration: Chinese Clinical Trial Registry, ChiCTR1900028627. |
| format | Article |
| id | doaj-art-a5f4729e68a341919db594b4b76f17f0 |
| institution | DOAJ |
| issn | 2213-4220 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj-art-a5f4729e68a341919db594b4b76f17f02025-08-20T03:02:29ZengElsevierIntegrative Medicine Research2213-42202025-03-0114110111710.1016/j.imr.2024.101117Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trialYing He0Gui-yuan Li1Chun-zhi Tang2Li-ming Lu3Guang-yi Xiong4Yi Gao5Juan Tong6Guang-en Zhong7Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, ChinaSouth China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, ChinaSouth China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Medical Biology and Statistics, School of Basic Medicine, Yunnan University of Chinese Medicine, Kunming, ChinaState Key Laboratory of Respiratory Diseases, National Clinical Research Center of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, Guangzhou, ChinaDepartment of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Corresponding authors at: Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong 510315, China (J. Tong); Department of Acupuncture Moxibustion and Rehabilitation, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, No. 13 Shiliugang Road, Haizhu District, Guangzhou, Guangdong 510315, China (G.-e. Zhong).Department of Acupuncture Moxibustion and Rehabilitation, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, Guangzhou, China; Corresponding authors at: Department of Traditional Chinese Medicine, The First Affiliated Hospital of Guangzhou Medical University, No. 151 Yanjiang Road, Yuexiu District, Guangzhou, Guangdong 510315, China (J. Tong); Department of Acupuncture Moxibustion and Rehabilitation, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, No. 13 Shiliugang Road, Haizhu District, Guangzhou, Guangdong 510315, China (G.-e. Zhong).Background: Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation. The purpose of this study was to evaluate the effectiveness of the use of penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance among COPD patients. Methods: A total of 85 patients were recruited and randomly assigned to receive treatment with either penetrating needles with electrical stimulation (PE) or non-penetrating needles with electrical stimulation (NPE) 3 times a week for 8 weeks, thereby resulting in a total of 24 treatments. Both groups underwent exercise training. The evaluations were conducted at baseline, after 14 treatments, and after 24 treatments. Results: The PE group showed significant improvement in the 6-minute walk distance (6MWD) after the 14th treatment. For the pulmonary function test, percentage of maximal voluntary ventilation (MVV%), maximal expiratory flow (MEF) after 75% of the forced vital capacity (FVC), MEF after 50% of FVC, and MEF after 25% of FVC were improved in the PE group, and especially MVV% was significantly greater than that in the NPE group. For cardiopulmonary exercise testing, percentage of oxygen consumption per kg body weight (VO2/kg), percentage of ventilation volume per minute (VE), maximal ventilation volume per minute (VEmax), ventilatory equivalent for oxygen (VE/VO2), and ventilatory equivalent for carbon dioxide (VE/VCO2) were significantly higher than the NPE group. The scores of COPD assessment test in the PE group significantly improved. Conclusion: Treatment with penetrating needles with electrical stimulation combined with exercise training may be clinically useful for COPD patients in relieving dyspnea and improving exercise tolerance. Trial Registration: Chinese Clinical Trial Registry, ChiCTR1900028627.http://www.sciencedirect.com/science/article/pii/S2213422024000970AcupunctureChronic obstructive pulmonary diseaseExercise trainingPulmonary rehabilitation |
| spellingShingle | Ying He Gui-yuan Li Chun-zhi Tang Li-ming Lu Guang-yi Xiong Yi Gao Juan Tong Guang-en Zhong Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial Integrative Medicine Research Acupuncture Chronic obstructive pulmonary disease Exercise training Pulmonary rehabilitation |
| title | Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial |
| title_full | Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial |
| title_fullStr | Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial |
| title_full_unstemmed | Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial |
| title_short | Comparison of penetrating needles and non-penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients: A single-blind randomized controlled trial |
| title_sort | comparison of penetrating needles and non penetrating needles with electrical stimulation combined with exercise training for relieving dyspnea and improving exercise tolerance in chronic obstructive pulmonary disease patients a single blind randomized controlled trial |
| topic | Acupuncture Chronic obstructive pulmonary disease Exercise training Pulmonary rehabilitation |
| url | http://www.sciencedirect.com/science/article/pii/S2213422024000970 |
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