Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis
<b>Background:</b> As the surgical repertoire for the management of sinonasal tumors evolves over time, an improved understanding of risks for postoperative complications is imperative. <b>Objectives:</b> To identify factors associated with 30-day postoperative complications...
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| Format: | Article |
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MDPI AG
2025-04-01
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| Series: | Sinusitis |
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| Online Access: | https://www.mdpi.com/2673-351X/9/1/8 |
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| author | Raymond J. So Hannan A. Qureshi Evelyn M. Leland Anirudh Saraswathula Murugappan Ramanathan Nyall R. London Nicholas R. Rowan |
| author_facet | Raymond J. So Hannan A. Qureshi Evelyn M. Leland Anirudh Saraswathula Murugappan Ramanathan Nyall R. London Nicholas R. Rowan |
| author_sort | Raymond J. So |
| collection | DOAJ |
| description | <b>Background:</b> As the surgical repertoire for the management of sinonasal tumors evolves over time, an improved understanding of risks for postoperative complications is imperative. <b>Objectives:</b> To identify factors associated with 30-day postoperative complications following the resection of sinonasal tumors. <b>Methods:</b> The National Surgical Quality Improvement Program (NSQIP) database was queried from 2005 to 2020 for patients undergoing open or endoscopic surgical resection of sinonasal tumors. A Cox proportional hazards model was used to identify factors associated with postoperative complications. Kaplan–Meier survival analyses and log-rank tests were used to compare time to complication onset. Frailty was defined as a 5-factor modified frailty index score > 2. <b>Results:</b> Of the 859 patients with sinonasal tumors, 539 (62.7%) were male, and the average age (± SD) was 59.3 ± 14.1 years. Postoperative complications were observed in 251 (29.2%) patients. The most common 30-day complications were bleeding requiring transfusions (n = 172; 20.0%) and ventilation longer than 48 h (n = 37; 4.3%). Frailty (aHR [95% CI]: 3.58 [1.80–7.12]), malignancy (3.43 [1.59–7.38]), and maxillary tumor location (2.40 [1.86–3.09]) were associated with greater risk for 30-day postoperative complications. Similarly, patients with frailty (χ<sup>2</sup> = 7.0; <i>p</i> = 0.008), malignant tumors (χ<sup>2</sup> = 13.4; <i>p</i> < 0.001), or maxillary sinus tumors (χ<sup>2</sup> = 34.6; <i>p</i> < 0.001) experienced earlier onset of postoperative complications. <b>Conclusions:</b> Frailty, malignancy status, and tumor location may modulate risk for 30-day postoperative complications following the resection of sinonasal tumors. These results may help to inform preoperative patient counseling and identify individuals at increased risk of postoperative complications. |
| format | Article |
| id | doaj-art-a5e55acfdbbf4c1eb0248666693a67a3 |
| institution | Kabale University |
| issn | 2673-351X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sinusitis |
| spelling | doaj-art-a5e55acfdbbf4c1eb0248666693a67a32025-08-20T03:27:43ZengMDPI AGSinusitis2673-351X2025-04-0191810.3390/sinusitis9010008Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP AnalysisRaymond J. So0Hannan A. Qureshi1Evelyn M. Leland2Anirudh Saraswathula3Murugappan Ramanathan4Nyall R. London5Nicholas R. Rowan6Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USADepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USADepartment of Otolaryngology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USADepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USADepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USADepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA<b>Background:</b> As the surgical repertoire for the management of sinonasal tumors evolves over time, an improved understanding of risks for postoperative complications is imperative. <b>Objectives:</b> To identify factors associated with 30-day postoperative complications following the resection of sinonasal tumors. <b>Methods:</b> The National Surgical Quality Improvement Program (NSQIP) database was queried from 2005 to 2020 for patients undergoing open or endoscopic surgical resection of sinonasal tumors. A Cox proportional hazards model was used to identify factors associated with postoperative complications. Kaplan–Meier survival analyses and log-rank tests were used to compare time to complication onset. Frailty was defined as a 5-factor modified frailty index score > 2. <b>Results:</b> Of the 859 patients with sinonasal tumors, 539 (62.7%) were male, and the average age (± SD) was 59.3 ± 14.1 years. Postoperative complications were observed in 251 (29.2%) patients. The most common 30-day complications were bleeding requiring transfusions (n = 172; 20.0%) and ventilation longer than 48 h (n = 37; 4.3%). Frailty (aHR [95% CI]: 3.58 [1.80–7.12]), malignancy (3.43 [1.59–7.38]), and maxillary tumor location (2.40 [1.86–3.09]) were associated with greater risk for 30-day postoperative complications. Similarly, patients with frailty (χ<sup>2</sup> = 7.0; <i>p</i> = 0.008), malignant tumors (χ<sup>2</sup> = 13.4; <i>p</i> < 0.001), or maxillary sinus tumors (χ<sup>2</sup> = 34.6; <i>p</i> < 0.001) experienced earlier onset of postoperative complications. <b>Conclusions:</b> Frailty, malignancy status, and tumor location may modulate risk for 30-day postoperative complications following the resection of sinonasal tumors. These results may help to inform preoperative patient counseling and identify individuals at increased risk of postoperative complications.https://www.mdpi.com/2673-351X/9/1/8sinonasal tumorspostoperative complicationsrisk factorsfrailtyobesitymaxillary artery |
| spellingShingle | Raymond J. So Hannan A. Qureshi Evelyn M. Leland Anirudh Saraswathula Murugappan Ramanathan Nyall R. London Nicholas R. Rowan Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis Sinusitis sinonasal tumors postoperative complications risk factors frailty obesity maxillary artery |
| title | Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis |
| title_full | Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis |
| title_fullStr | Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis |
| title_full_unstemmed | Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis |
| title_short | Factors Associated with Postoperative Complications Following Resection of Sinonasal Tumors: A NSQIP Analysis |
| title_sort | factors associated with postoperative complications following resection of sinonasal tumors a nsqip analysis |
| topic | sinonasal tumors postoperative complications risk factors frailty obesity maxillary artery |
| url | https://www.mdpi.com/2673-351X/9/1/8 |
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