Integrative multi-omic analysis of NLRP3 inflammasome dysregulation and subtyping for personalized treatment in acute myeloid leukemia

Integrative multi-omic analysis of NLRP3 inflammasome dysregulation and subtyping for personalized treatment in acute myeloid leukemia

Abstract Acute myeloid leukemia (AML) is a devastating form of blood cancer characterized by uncontrolled growth and impaired maturation of myeloid precursor cells in the bone marrow. Despite advancements in treatment strategies, the prognosis for AML patients remains poor. The NLRP3 inflammasome, a...

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Bibliographic Details
Main Authors: Hong Zhang, Linlin Yang, Yukexin Liu, Dongju Wang, Liming Shi, Changyu Tian
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Acute myeloid leukemia
NLRP3 inflammasome
Tumor immune microenvironment
Prognosis
Drug response
Online Access:https://doi.org/10.1007/s12672-025-02383-9
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