Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP

Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP

ABSTRACT Pulmonary arterial endothelial and smooth muscle cell homeostasis is regulated through the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF‐β) receptor pathways. Pathway imbalance results in pulmonary hypertension (PH). Each pathway has ligands and modulators influe...

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Bibliographic Details
Main Authors: Edward C. Kirkpatrick, Stephanie Handler, Melodee Liegl, Amy Y. Pan, G. Ganesh Konduri, Todd M. Gudausky, Adeleye J. Afolayan
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Pulmonary Circulation
Subjects:
cardiac catheterization
ELISA
TGF‐β pathway
Online Access:https://doi.org/10.1002/pul2.70068
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