Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation

Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation

Abstract Background Low-grade glioma (LGG) is a primary brain tumor with relatively low malignancy. NCOA4 is a key regulator of ferritinophagy-related processes and is involved in the occurrence and development of many cancers. However, the role of NCOA4 in LGG remains poorly understood. Methods Thi...

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Bibliographic Details
Main Authors: Guangtang Chen, Xueping Shi, Rukai Jiao, Jiacai Qian, Xiaolin Du, Jian Liu, Xi Zeng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Neurology
Subjects:
Low-grade glioma
NCOA4
Ferroptosis
Prognosis
Biomarker
Online Access:https://doi.org/10.1186/s12883-025-04036-4
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