Distinct sex differences in ethanol consumption and operant self-administration in C57BL/6J mice with uniform regulation by glutamate AMPAR activity

Distinct sex differences in ethanol consumption and operant self-administration in C57BL/6J mice with uniform regulation by glutamate AMPAR activity

IntroductionConsidering sex as a biological variable (SABV) in preclinical research can enhance understanding of the neurobiology of alcohol use disorder (AUD). However, the behavioral and neural mechanisms underlying sex-specific differences remain unclear. This study aims to elucidate SABV in etha...

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Bibliographic Details
Main Authors:	Sara Faccidomo, Vallari R. Eastman, Taruni S. Santanam, Katarina S. Swaim, Seth M. Taylor, Clyde W. Hodge
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Behavioral Neuroscience
Subjects:	sex as a biological variable ethanol alcohol drinking glutamate AMPA receptors operant self-administration
Online Access:	https://www.frontiersin.org/articles/10.3389/fnbeh.2024.1498201/full
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