L-DOPA Uptake in Astrocytic Endfeet Enwrapping Blood Vessels in Rat Brain

L-DOPA Uptake in Astrocytic Endfeet Enwrapping Blood Vessels in Rat Brain

Astrocyte endfeet surround brain blood vessels and can play a role in the delivery of therapeutic drugs for Parkinson’s disease. However, there is no previous evidence of the presence of LAT transporter for L-DOPA in brain astrocytes except in culture. Using systemic L-DOPA administration and a comb...

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Bibliographic Details
Main Authors: M. Y. Inyushin, A. Huertas, Y. V. Kucheryavykh, L. Y. Kucheryavykh, V. Tsydzik, P. Sanabria, M. J. Eaton, S. N. Skatchkov, L. V. Rojas, W. D. Wessinger
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2012/321406
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