Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis

Recurrent pleural effusions occurring in association with immunoglobulin light chain amyloidosis and not associated with amyloid cardiomyopathy are rare. These portend an overall poor prognosis with mean survival time of approximately 1.8 months. We hereby report a case of a 59-year-old Caucasian fe...

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Main Authors: Lauren Tada, Humayun Anjum, W. Kenneth Linville, Salim Surani
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2015/421201
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author Lauren Tada
Humayun Anjum
W. Kenneth Linville
Salim Surani
author_facet Lauren Tada
Humayun Anjum
W. Kenneth Linville
Salim Surani
author_sort Lauren Tada
collection DOAJ
description Recurrent pleural effusions occurring in association with immunoglobulin light chain amyloidosis and not associated with amyloid cardiomyopathy are rare. These portend an overall poor prognosis with mean survival time of approximately 1.8 months. We hereby report a case of a 59-year-old Caucasian female with recurrent pleural effusions and an ultimate diagnosis of pulmonary amyloidosis in association with plasma cell myeloma. The optimal treatment for recurrent pleural effusions in amyloidosis has not been determined; however, our patient responded to therapy with Cyclophosphamide-Bortezomib- (Velcade-) Dexamethasone (CyBorD) and had no repeat hospitalizations or recurrence of pleural effusion at four-month follow-up after initiation of therapy.
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institution Kabale University
issn 2090-6846
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language English
publishDate 2015-01-01
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series Case Reports in Pulmonology
spelling doaj-art-a594ae1f9b5f4facb73c6b5c017a0bb82025-02-03T01:02:48ZengWileyCase Reports in Pulmonology2090-68462090-68542015-01-01201510.1155/2015/421201421201Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary AmyloidosisLauren Tada0Humayun Anjum1W. Kenneth Linville2Salim Surani3Corpus Christi Medical Center, 7002 William Drive, Corpus Christi, TX 78412, USAPulmonary & Critical Care, Bay Area Medical Center, 7002 William Drive, Corpus Christi, TX 78412, USAPathology Department, Bay Area Medical Center, 7002 William Drive, Corpus Christi, TX 78412, USATexas A&M University, 1177 West Wheeler Avenue, Aransas Pass, TX 78336, USARecurrent pleural effusions occurring in association with immunoglobulin light chain amyloidosis and not associated with amyloid cardiomyopathy are rare. These portend an overall poor prognosis with mean survival time of approximately 1.8 months. We hereby report a case of a 59-year-old Caucasian female with recurrent pleural effusions and an ultimate diagnosis of pulmonary amyloidosis in association with plasma cell myeloma. The optimal treatment for recurrent pleural effusions in amyloidosis has not been determined; however, our patient responded to therapy with Cyclophosphamide-Bortezomib- (Velcade-) Dexamethasone (CyBorD) and had no repeat hospitalizations or recurrence of pleural effusion at four-month follow-up after initiation of therapy.http://dx.doi.org/10.1155/2015/421201
spellingShingle Lauren Tada
Humayun Anjum
W. Kenneth Linville
Salim Surani
Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis
Case Reports in Pulmonology
title Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis
title_full Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis
title_fullStr Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis
title_full_unstemmed Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis
title_short Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis
title_sort recurrent pleural effusions occurring in association with primary pulmonary amyloidosis
url http://dx.doi.org/10.1155/2015/421201
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AT wkennethlinville recurrentpleuraleffusionsoccurringinassociationwithprimarypulmonaryamyloidosis
AT salimsurani recurrentpleuraleffusionsoccurringinassociationwithprimarypulmonaryamyloidosis