First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces

Based on first-principles calculations, the stability of three adsorption configurations of glycine on the (100) surface of diamonds was studied, leading to an investigation into the surface-enhanced Raman scattering (SERS) effect of the diamond substrate. The results showed that the carboxyl-termin...

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Main Authors: Shiyang Sun, Chi Zhang, Peilun An, Pingping Xu, Wenxing Zhang, Yuan Ren, Xin Tan, Jinlong Yu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Nanomaterials
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Online Access:https://www.mdpi.com/2079-4991/15/7/502
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author Shiyang Sun
Chi Zhang
Peilun An
Pingping Xu
Wenxing Zhang
Yuan Ren
Xin Tan
Jinlong Yu
author_facet Shiyang Sun
Chi Zhang
Peilun An
Pingping Xu
Wenxing Zhang
Yuan Ren
Xin Tan
Jinlong Yu
author_sort Shiyang Sun
collection DOAJ
description Based on first-principles calculations, the stability of three adsorption configurations of glycine on the (100) surface of diamonds was studied, leading to an investigation into the surface-enhanced Raman scattering (SERS) effect of the diamond substrate. The results showed that the carboxyl-terminated adsorption configuration (CAR) was the most stable and shortest interface distance compared to other configurations. This stability was primarily attributed to the formation of strong polar covalent bonds between the carboxyl O atoms and the surface C atoms of the (100) surface of diamonds. These results were further corroborated by first-principles molecular dynamics simulations. Within the temperature range of 300 to 500 K, the glycine molecules in the carboxyl-terminated adjacent-dimer phenyl-like (CAR) configuration exhibited only simple thermal vibrations with varying amplitudes. In contrast, the metastable ATO and carboxyl-terminated trans-dimer phenyl-like ring (CTR) configurations were observed to gradually transform into benzene-ring-like structures akin to the CAR configuration. After adsorption, the intensity of glycine’s characteristic peaks increased substantially, accompanied by a blue shift phenomenon. Notably, the characteristic peaks related to the carboxyl and amino groups exhibited the highest enhancement amplitude, exceeding 200 times, with an average enhancement amplitude exceeding 50 times. The diamond substrate, with its excellent adsorption properties and strong surface Raman spectroscopy characteristics, represents a highly promising candidate in the field of biomedicine.
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spelling doaj-art-a56e9d8b8cf149d7b51ec39948f98a442025-08-20T02:15:47ZengMDPI AGNanomaterials2079-49912025-03-0115750210.3390/nano15070502First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond SurfacesShiyang Sun0Chi Zhang1Peilun An2Pingping Xu3Wenxing Zhang4Yuan Ren5Xin Tan6Jinlong Yu7School of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaSchool of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaSchool of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaSchool of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaSchool of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaSchool of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaSchool of Mechanical Engineering, Inner Mongolia University of Science & Technology, Baotou 014010, ChinaBeiben Trucks Group Co., Ltd., Baotou 014010, ChinaBased on first-principles calculations, the stability of three adsorption configurations of glycine on the (100) surface of diamonds was studied, leading to an investigation into the surface-enhanced Raman scattering (SERS) effect of the diamond substrate. The results showed that the carboxyl-terminated adsorption configuration (CAR) was the most stable and shortest interface distance compared to other configurations. This stability was primarily attributed to the formation of strong polar covalent bonds between the carboxyl O atoms and the surface C atoms of the (100) surface of diamonds. These results were further corroborated by first-principles molecular dynamics simulations. Within the temperature range of 300 to 500 K, the glycine molecules in the carboxyl-terminated adjacent-dimer phenyl-like (CAR) configuration exhibited only simple thermal vibrations with varying amplitudes. In contrast, the metastable ATO and carboxyl-terminated trans-dimer phenyl-like ring (CTR) configurations were observed to gradually transform into benzene-ring-like structures akin to the CAR configuration. After adsorption, the intensity of glycine’s characteristic peaks increased substantially, accompanied by a blue shift phenomenon. Notably, the characteristic peaks related to the carboxyl and amino groups exhibited the highest enhancement amplitude, exceeding 200 times, with an average enhancement amplitude exceeding 50 times. The diamond substrate, with its excellent adsorption properties and strong surface Raman spectroscopy characteristics, represents a highly promising candidate in the field of biomedicine.https://www.mdpi.com/2079-4991/15/7/502diamond surfaceglycineSERSAIMDfirst-principles calculation
spellingShingle Shiyang Sun
Chi Zhang
Peilun An
Pingping Xu
Wenxing Zhang
Yuan Ren
Xin Tan
Jinlong Yu
First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces
Nanomaterials
diamond surface
glycine
SERS
AIMD
first-principles calculation
title First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces
title_full First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces
title_fullStr First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces
title_full_unstemmed First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces
title_short First-Principles Calculations for Glycine Adsorption Dynamics and Surface-Enhanced Raman Spectroscopy on Diamond Surfaces
title_sort first principles calculations for glycine adsorption dynamics and surface enhanced raman spectroscopy on diamond surfaces
topic diamond surface
glycine
SERS
AIMD
first-principles calculation
url https://www.mdpi.com/2079-4991/15/7/502
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