On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides
Pancreatic islets in type 2 diabetes mellitus (T2DM) patients are characterized by reduced β-cells mass and diffuse extracellular amyloidosis. Amyloid deposition involves the islet amyloid polypeptide (IAPP), a neuropancreatic hormone cosecreted with insulin by β-cells. IAPP is phy...
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Main Authors: | Marianna Flora Tomasello, Alessandro Sinopoli, Giuseppe Pappalardo |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2015/918573 |
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