Redefining Lactose as a Conditional Prebiotic

Lactose in dairy products is maldigested by up to 70% to 75% of the world's population and many people may therefore suffer symptoms reminiscent of irritable bowel syndrome. As a result, most research to date has concentrated on ways of improving lactose tolerance to enhance dairy as a source o...

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Main Author: Andrew Szilagyi
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2004/350732
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author Andrew Szilagyi
author_facet Andrew Szilagyi
author_sort Andrew Szilagyi
collection DOAJ
description Lactose in dairy products is maldigested by up to 70% to 75% of the world's population and many people may therefore suffer symptoms reminiscent of irritable bowel syndrome. As a result, most research to date has concentrated on ways of improving lactose tolerance to enhance dairy as a source of nutrition. However, research on other possible benefits of lactose and its maldigestion has lagged. In view of an exponential growth in the understanding of intestinal microfloral host interactions and the expanding therapeutical potential of probiotics, a reassessment of the role of lactose as a potential prebiotic in lactase nonpersistent subjects is required. Gibson and Roberfroid introduced the concept of prebiotics and outlined definitive requirements for such a compound. The present article examines scientific and clinical knowledge about the properties of lactose and argues that in lactase nonpersistent subjects, lactose qualifies as a prebiotic.
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spelling doaj-art-a551992869c6430bad250390bf20ad132025-02-03T05:53:42ZengWileyCanadian Journal of Gastroenterology0835-79002004-01-0118316316710.1155/2004/350732Redefining Lactose as a Conditional PrebioticAndrew SzilagyiLactose in dairy products is maldigested by up to 70% to 75% of the world's population and many people may therefore suffer symptoms reminiscent of irritable bowel syndrome. As a result, most research to date has concentrated on ways of improving lactose tolerance to enhance dairy as a source of nutrition. However, research on other possible benefits of lactose and its maldigestion has lagged. In view of an exponential growth in the understanding of intestinal microfloral host interactions and the expanding therapeutical potential of probiotics, a reassessment of the role of lactose as a potential prebiotic in lactase nonpersistent subjects is required. Gibson and Roberfroid introduced the concept of prebiotics and outlined definitive requirements for such a compound. The present article examines scientific and clinical knowledge about the properties of lactose and argues that in lactase nonpersistent subjects, lactose qualifies as a prebiotic.http://dx.doi.org/10.1155/2004/350732
spellingShingle Andrew Szilagyi
Redefining Lactose as a Conditional Prebiotic
Canadian Journal of Gastroenterology
title Redefining Lactose as a Conditional Prebiotic
title_full Redefining Lactose as a Conditional Prebiotic
title_fullStr Redefining Lactose as a Conditional Prebiotic
title_full_unstemmed Redefining Lactose as a Conditional Prebiotic
title_short Redefining Lactose as a Conditional Prebiotic
title_sort redefining lactose as a conditional prebiotic
url http://dx.doi.org/10.1155/2004/350732
work_keys_str_mv AT andrewszilagyi redefininglactoseasaconditionalprebiotic