Performance of HPV genotyping and GYPC methylation as a triage strategy for HPV-positive women with normal or minimal cytological findings

Performance of HPV genotyping and GYPC methylation as a triage strategy for HPV-positive women with normal or minimal cytological findings

ObjectiveHigh-risk human papillomavirus (HR-HPV) screening has increased colposcopy referrals, particularly for women with HR-HPV positivity but no intraepithelial lesion or malignancy (NILM) and those with atypical squamous cells of undetermined significance (ASC-US). A fraction of low-grade squamo...

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Bibliographic Details
Main Authors: Saiping Mao, Xing Fan, Li Yang, Hongtao Li, Dandan Liu, Xiaoli He, Xiaoli Wang, Fang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Medicine
Subjects:
cervical screening
cervical intraepithelial neoplasia
GYPC methylation
high-risk human papillomavirus
absolute risk
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1575887/full
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