Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice
Tropomyosin (TM) in shrimp is one of the predominant causes of food allergy around the world. In the present study, the effect of seabuckthorn juice against TM -induced shrimp allergy was investigated in BALB/c mice. Allergic symptoms, spleen index, intestinal section and diarrhea were measured in s...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2023-05-01
|
| Series: | Food Science and Human Wellness |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453022001999 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832546479992995840 |
|---|---|
| author | Hong Ren Xiaofan Zhu Shiyu Zhai Xiaoping Feng Zhuomin Yan Jiao Sun Ye Liu Zhenpeng Gao Fangyu Long |
| author_facet | Hong Ren Xiaofan Zhu Shiyu Zhai Xiaoping Feng Zhuomin Yan Jiao Sun Ye Liu Zhenpeng Gao Fangyu Long |
| author_sort | Hong Ren |
| collection | DOAJ |
| description | Tropomyosin (TM) in shrimp is one of the predominant causes of food allergy around the world. In the present study, the effect of seabuckthorn juice against TM -induced shrimp allergy was investigated in BALB/c mice. Allergic symptoms, spleen index, intestinal section and diarrhea were measured in shrimp allergy mice. As the results, seabuckthorn juice suppressed the lesions in jejunum tissue, diarrhea and allergic symptoms in shrimp allergy mice. Seabuckthorn juice also reduced serum concentrations of tumor necrosis factor-α (TNF-α) as well as immunoglobulin E (IgE) and stimulated the secretion of interleukin-10 (IL-10) in mice with shrimp allergy. Taken together, our findings suggest that increased IL-10 by seabuckthorn juice inhibits Th2 cytokine production to suppress shrimp allergic symptoms. Furthermore, seabuckthorn juice also regulates shrimp allergy by reducing jejunum lesions, inhibiting levels of TNF-α and IgE. |
| format | Article |
| id | doaj-art-a534a9bb55a341649440a4f792b5594b |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2023-05-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-a534a9bb55a341649440a4f792b5594b2025-02-03T06:53:35ZengTsinghua University PressFood Science and Human Wellness2213-45302023-05-01123783788Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy miceHong Ren0Xiaofan Zhu1Shiyu Zhai2Xiaoping Feng3Zhuomin Yan4Jiao Sun5Ye Liu6Zhenpeng Gao7Fangyu Long8College of Food Science and Engineering, Northwest A&F University, Yangling 712100, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, ChinaDepartment of Breast Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, ChinaChina-Canada Joint Laboratory of Food Nutrition and Health (Beijing), Beijing Technology & Business University, Beijing 100048, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, ChinaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, China; Corresponding author at: College of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.Tropomyosin (TM) in shrimp is one of the predominant causes of food allergy around the world. In the present study, the effect of seabuckthorn juice against TM -induced shrimp allergy was investigated in BALB/c mice. Allergic symptoms, spleen index, intestinal section and diarrhea were measured in shrimp allergy mice. As the results, seabuckthorn juice suppressed the lesions in jejunum tissue, diarrhea and allergic symptoms in shrimp allergy mice. Seabuckthorn juice also reduced serum concentrations of tumor necrosis factor-α (TNF-α) as well as immunoglobulin E (IgE) and stimulated the secretion of interleukin-10 (IL-10) in mice with shrimp allergy. Taken together, our findings suggest that increased IL-10 by seabuckthorn juice inhibits Th2 cytokine production to suppress shrimp allergic symptoms. Furthermore, seabuckthorn juice also regulates shrimp allergy by reducing jejunum lesions, inhibiting levels of TNF-α and IgE.http://www.sciencedirect.com/science/article/pii/S2213453022001999ShrimpSeabuckthorn juiceAllergyBALB/c mouse model |
| spellingShingle | Hong Ren Xiaofan Zhu Shiyu Zhai Xiaoping Feng Zhuomin Yan Jiao Sun Ye Liu Zhenpeng Gao Fangyu Long Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice Food Science and Human Wellness Shrimp Seabuckthorn juice Allergy BALB/c mouse model |
| title | Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice |
| title_full | Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice |
| title_fullStr | Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice |
| title_full_unstemmed | Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice |
| title_short | Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice |
| title_sort | seabuckthorn juice alleviates allergic symptoms in shrimp induced food allergy mice |
| topic | Shrimp Seabuckthorn juice Allergy BALB/c mouse model |
| url | http://www.sciencedirect.com/science/article/pii/S2213453022001999 |
| work_keys_str_mv | AT hongren seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT xiaofanzhu seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT shiyuzhai seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT xiaopingfeng seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT zhuominyan seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT jiaosun seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT yeliu seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT zhenpenggao seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice AT fangyulong seabuckthornjuicealleviatesallergicsymptomsinshrimpinducedfoodallergymice |