Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review
Background. Primary splenic angiosarcoma is a very rare mesenchymal malignant tumor associated with a poor prognosis due to its high metastatic potential. This disease can be easily neglected and spontaneous splenic rupture is a frequent manifestation at the time of diagnosis leading to a poor outco...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2017/6256102 |
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| author | Sara Coppola Andrea Leva Fabio Pagni Simone Famularo Luca Gianotti |
| author_facet | Sara Coppola Andrea Leva Fabio Pagni Simone Famularo Luca Gianotti |
| author_sort | Sara Coppola |
| collection | DOAJ |
| description | Background. Primary splenic angiosarcoma is a very rare mesenchymal malignant tumor associated with a poor prognosis due to its high metastatic potential. This disease can be easily neglected and spontaneous splenic rupture is a frequent manifestation at the time of diagnosis leading to a poor outcome because of peritoneal dissemination. Case Presentation. We describe the case of a 49-year-old man who presented with asthenia, left upper quadrant abdominal pain, and anemia. Computerized tomography scan showed an enlarged spleen with no nodules and a nontraumatic rupture of the splenic capsule. Splenectomy was performed on account of the severe anemia and histopathology examination showed a primary angiosarcoma. Conclusions. Splenic angiosarcoma should be considered as one of the differential diagnoses in patients with nontraumatic spleen rupture and a specific previous medical history. Regrettably, splenectomy allows for a definitive diagnosis but not a curative treatment. |
| format | Article |
| id | doaj-art-a52de564173c4c7f9a715eb2ebff4f42 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-a52de564173c4c7f9a715eb2ebff4f422025-02-03T01:10:46ZengWileyCase Reports in Surgery2090-69002090-69192017-01-01201710.1155/2017/62561026256102Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature ReviewSara Coppola0Andrea Leva1Fabio Pagni2Simone Famularo3Luca Gianotti4School of Medicine and Surgery, Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, ItalySchool of Medicine and Surgery, Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, ItalySchool of Medicine and Surgery, Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, ItalySchool of Medicine and Surgery, Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, ItalySchool of Medicine and Surgery, Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, ItalyBackground. Primary splenic angiosarcoma is a very rare mesenchymal malignant tumor associated with a poor prognosis due to its high metastatic potential. This disease can be easily neglected and spontaneous splenic rupture is a frequent manifestation at the time of diagnosis leading to a poor outcome because of peritoneal dissemination. Case Presentation. We describe the case of a 49-year-old man who presented with asthenia, left upper quadrant abdominal pain, and anemia. Computerized tomography scan showed an enlarged spleen with no nodules and a nontraumatic rupture of the splenic capsule. Splenectomy was performed on account of the severe anemia and histopathology examination showed a primary angiosarcoma. Conclusions. Splenic angiosarcoma should be considered as one of the differential diagnoses in patients with nontraumatic spleen rupture and a specific previous medical history. Regrettably, splenectomy allows for a definitive diagnosis but not a curative treatment.http://dx.doi.org/10.1155/2017/6256102 |
| spellingShingle | Sara Coppola Andrea Leva Fabio Pagni Simone Famularo Luca Gianotti Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review Case Reports in Surgery |
| title | Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review |
| title_full | Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review |
| title_fullStr | Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review |
| title_full_unstemmed | Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review |
| title_short | Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review |
| title_sort | demanding diagnosis of splenic angiosarcoma as cause of delayed treatment of spontaneous splenic rupture a case report and literature review |
| url | http://dx.doi.org/10.1155/2017/6256102 |
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