MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells

MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells

IntroductionThe role of miRNAs in regulating variable molecular functions has been sought by scientists for its promising utility in regulating the immune response and, hence, in treating various diseases. In hepatocellular carcinoma (HCC) specifically, a reduction in the number and efficiency of ci...

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Main Authors: Rowan Abdelbary, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
microRNAs (miRNAs)
miR-216a-3p
hepatocellular carcinoma (HCC)
natural killer (NK) cells
tumor necrosis factor-alpha (TNF-alpha)
interferon-gamma (IFN-gamma)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1523068/full
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