TphPMF: A microbiome data imputation method using hierarchical Bayesian Probabilistic Matrix Factorization.

In microbiome research, data sparsity represents a prevalent and formidable challenge. Sparse data not only compromises the accuracy of statistical analyses but also conceals critical biological relationships, thereby undermining the reliability of the conclusions. To tackle this issue, we introduce...

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Bibliographic Details
Main Authors: Xinyu Han, Kai Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012858
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