A Survey of Insulin-Dependent Diabetes—Part II: Control Methods

We survey blood glucose control schemes for insulin-dependent diabetes therapies and systems. These schemes largely rely on mathematical models of the insulin-glucose relations, and these models are typically derived in an empirical or fundamental way. In an empirical way, the experimental insulin i...

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Main Authors: Daisuke Takahashi, Yang Xiao, Fei Hu
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:International Journal of Telemedicine and Applications
Online Access:http://dx.doi.org/10.1155/2008/739385
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author Daisuke Takahashi
Yang Xiao
Fei Hu
author_facet Daisuke Takahashi
Yang Xiao
Fei Hu
author_sort Daisuke Takahashi
collection DOAJ
description We survey blood glucose control schemes for insulin-dependent diabetes therapies and systems. These schemes largely rely on mathematical models of the insulin-glucose relations, and these models are typically derived in an empirical or fundamental way. In an empirical way, the experimental insulin inputs and resulting blood-glucose outputs are used to generate a mathematical model, which includes a couple of equations approximating a very complex system. On the other hand, the insulin-glucose relation is also explained from the well-known facts of other biological mechanisms. Since these mechanisms are more or less related with each other, a mathematical model of the insulin-glucose system can be derived from these surrounding relations. This kind of method of the mathematical model derivation is called a fundamental method. Along with several mathematical models, researchers develop autonomous systems whether they involve medical devices or not to compensate metabolic disorders and these autonomous systems employ their own control methods. Basically, in insulin-dependent diabetes therapies, control methods are classified into three categories: open-loop, closed-loop, and partially closed-loop controls. The main difference among these methods is how much the systems are open to the outside people.
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spelling doaj-art-a4f52e3b83644f039a751b07c7ec16fe2025-02-03T06:44:45ZengWileyInternational Journal of Telemedicine and Applications1687-64151687-64232008-01-01200810.1155/2008/739385739385A Survey of Insulin-Dependent Diabetes—Part II: Control MethodsDaisuke Takahashi0Yang Xiao1Fei Hu2Department of Computer Science, The University of Alabama, Tuscaloosa, AL 35487, USADepartment of Computer Science, The University of Alabama, Tuscaloosa, AL 35487, USAComputer Engineering Department, Rochester Institute of Technology, Rochester, NY 14623, USAWe survey blood glucose control schemes for insulin-dependent diabetes therapies and systems. These schemes largely rely on mathematical models of the insulin-glucose relations, and these models are typically derived in an empirical or fundamental way. In an empirical way, the experimental insulin inputs and resulting blood-glucose outputs are used to generate a mathematical model, which includes a couple of equations approximating a very complex system. On the other hand, the insulin-glucose relation is also explained from the well-known facts of other biological mechanisms. Since these mechanisms are more or less related with each other, a mathematical model of the insulin-glucose system can be derived from these surrounding relations. This kind of method of the mathematical model derivation is called a fundamental method. Along with several mathematical models, researchers develop autonomous systems whether they involve medical devices or not to compensate metabolic disorders and these autonomous systems employ their own control methods. Basically, in insulin-dependent diabetes therapies, control methods are classified into three categories: open-loop, closed-loop, and partially closed-loop controls. The main difference among these methods is how much the systems are open to the outside people.http://dx.doi.org/10.1155/2008/739385
spellingShingle Daisuke Takahashi
Yang Xiao
Fei Hu
A Survey of Insulin-Dependent Diabetes—Part II: Control Methods
International Journal of Telemedicine and Applications
title A Survey of Insulin-Dependent Diabetes—Part II: Control Methods
title_full A Survey of Insulin-Dependent Diabetes—Part II: Control Methods
title_fullStr A Survey of Insulin-Dependent Diabetes—Part II: Control Methods
title_full_unstemmed A Survey of Insulin-Dependent Diabetes—Part II: Control Methods
title_short A Survey of Insulin-Dependent Diabetes—Part II: Control Methods
title_sort survey of insulin dependent diabetes part ii control methods
url http://dx.doi.org/10.1155/2008/739385
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