Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes

Background. We investigated the effect of laparoscopic sleeve gastrectomy (LSG) on morbidly obese diabetics and examined the short-term impact of LSG on diabetic medication cost. Methods. A prospective database of consecutive bariatric patients was reviewed. Morbidly obese patients with type 2 diab...

Full description

Saved in:
Bibliographic Details
Main Authors: Bethany J. Slater, Nina Bellatorre, Dan Eisenberg
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2011/350523
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832567537467916288
author Bethany J. Slater
Nina Bellatorre
Dan Eisenberg
author_facet Bethany J. Slater
Nina Bellatorre
Dan Eisenberg
author_sort Bethany J. Slater
collection DOAJ
description Background. We investigated the effect of laparoscopic sleeve gastrectomy (LSG) on morbidly obese diabetics and examined the short-term impact of LSG on diabetic medication cost. Methods. A prospective database of consecutive bariatric patients was reviewed. Morbidly obese patients with type 2 diabetes who underwent LSG were included in the study. Age, gender, body mass index (BMI), diabetic medication use, glucose, insulin, and HbA1c levels were documented preoperatively, and at 2 weeks, 2 months, 6 months, and 12 months postoperatively. Insulin resistance was estimated using the homeostatic model assessment (HOMA). Use and cost of diabetic medications were followed. Results. Of 178 patients, 22 were diabetics who underwent LSG. Diabetes remission was observed in 62% of patients within 2 months and in 75% of patients within 12 months. HOMA-IR improved after only two weeks following surgery (16.5 versus 6.6, 𝑃<0.001). Average number of diabetic medications decreased from 2.2 to <1, within 2 weeks after surgery; corresponding to a diabetes medication cost savings of 80%, 91%, 99%, and 99.7% after 2 weeks, 2 months, 6 months, and 12 months, respectively. Conclusion. Morbidly obese patients with diabetes who undergo LSG have high rates of diabetes remission early after surgery. This translates to a significant medication cost savings.
format Article
id doaj-art-a4edc6263ec0473a8ad211d61ba49217
institution Kabale University
issn 2090-0708
2090-0716
language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series Journal of Obesity
spelling doaj-art-a4edc6263ec0473a8ad211d61ba492172025-02-03T01:01:14ZengWileyJournal of Obesity2090-07082090-07162011-01-01201110.1155/2011/350523350523Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 DiabetesBethany J. Slater0Nina Bellatorre1Dan Eisenberg2Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305-2200, USADepartment of Surgery, VA Palo Alto Health Care System, 3801 Miranda Avenue, GS 112, Palo Alto, CA 94304, USADepartment of Surgery, Stanford University School of Medicine, Stanford, CA 94305-2200, USABackground. We investigated the effect of laparoscopic sleeve gastrectomy (LSG) on morbidly obese diabetics and examined the short-term impact of LSG on diabetic medication cost. Methods. A prospective database of consecutive bariatric patients was reviewed. Morbidly obese patients with type 2 diabetes who underwent LSG were included in the study. Age, gender, body mass index (BMI), diabetic medication use, glucose, insulin, and HbA1c levels were documented preoperatively, and at 2 weeks, 2 months, 6 months, and 12 months postoperatively. Insulin resistance was estimated using the homeostatic model assessment (HOMA). Use and cost of diabetic medications were followed. Results. Of 178 patients, 22 were diabetics who underwent LSG. Diabetes remission was observed in 62% of patients within 2 months and in 75% of patients within 12 months. HOMA-IR improved after only two weeks following surgery (16.5 versus 6.6, 𝑃<0.001). Average number of diabetic medications decreased from 2.2 to <1, within 2 weeks after surgery; corresponding to a diabetes medication cost savings of 80%, 91%, 99%, and 99.7% after 2 weeks, 2 months, 6 months, and 12 months, respectively. Conclusion. Morbidly obese patients with diabetes who undergo LSG have high rates of diabetes remission early after surgery. This translates to a significant medication cost savings.http://dx.doi.org/10.1155/2011/350523
spellingShingle Bethany J. Slater
Nina Bellatorre
Dan Eisenberg
Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
Journal of Obesity
title Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
title_full Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
title_fullStr Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
title_full_unstemmed Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
title_short Early Postoperative Outcomes and Medication Cost Savings after Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Type 2 Diabetes
title_sort early postoperative outcomes and medication cost savings after laparoscopic sleeve gastrectomy in morbidly obese patients with type 2 diabetes
url http://dx.doi.org/10.1155/2011/350523
work_keys_str_mv AT bethanyjslater earlypostoperativeoutcomesandmedicationcostsavingsafterlaparoscopicsleevegastrectomyinmorbidlyobesepatientswithtype2diabetes
AT ninabellatorre earlypostoperativeoutcomesandmedicationcostsavingsafterlaparoscopicsleevegastrectomyinmorbidlyobesepatientswithtype2diabetes
AT daneisenberg earlypostoperativeoutcomesandmedicationcostsavingsafterlaparoscopicsleevegastrectomyinmorbidlyobesepatientswithtype2diabetes