The capsaicin receptor TRPV1 reduces sepsis-associated brain injury in mice by inhibiting pyroptosis

Abstract Purpose Sepsis is a life-threatening disorder marked by organ dysfunction due to infection. Transient receptor potential vanilloid 1 (TRPV1) is a non-selective, ligand-gated cation channel activated by multiple stimuli. This study investigates the role of TRPV1 in sepsis-associated encephal...

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Bibliographic Details
Main Authors: Menghong Long, Zhenyu Hu, Feiyu Long, Yingxu Chen, Li Liu, Maohua Wang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Anesthesiology and Perioperative Science
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Online Access:https://doi.org/10.1007/s44254-025-00115-4
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