Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023
Abstract The landscape of scientific research in Latin America (LA), particularly in the realms of the Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutic models (PBPM), is a mosaic of varied contributions, collaborations, and specializations. This study examines r...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidade de São Paulo
2025-01-01
|
| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502025000100808&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832592520898412544 |
|---|---|
| author | Marx Ribeiro Juliana Cordeiro Cardoso José Eduardo Severino Martins Aline Ferreira Pinto Eliana Maria Barbosa Souto Patricia Severino |
| author_facet | Marx Ribeiro Juliana Cordeiro Cardoso José Eduardo Severino Martins Aline Ferreira Pinto Eliana Maria Barbosa Souto Patricia Severino |
| author_sort | Marx Ribeiro |
| collection | DOAJ |
| description | Abstract The landscape of scientific research in Latin America (LA), particularly in the realms of the Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutic models (PBPM), is a mosaic of varied contributions, collaborations, and specializations. This study examines research production in the region using data from the Scopus and PubMed databases collected between 2011 and 2023. Brazil stands out as a prominent country in terms of the quantity of publications. When considering thematic specialization, Colombia cones first as the country with the greatest Relative Specialization Index (RSI), followed by Brazil, Cuba, Uruguay, Mexico, and Argentina. Regarding internationalization, Brazil and Mexico are currently exerting significant influence, particularly through their increasing cooperation with the United States and Europe. Interestingly, there is a lack of cooperation inside Latin America at the regional level. Regarding the contribution of Latin-American institutions, the State University of Maringá leads in number of publications, followed by the University of São Paulo and the Federal University of São Paulo. In this work, we analyzed the strengths and weaknesses of LA’s scientific contributions, offering a roadmap for future collaborative and specialized efforts in the field of PBPK and PBBM. |
| format | Article |
| id | doaj-art-a4b8399f7cd54cbc90ade985cf9e1191 |
| institution | Kabale University |
| issn | 2175-9790 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj-art-a4b8399f7cd54cbc90ade985cf9e11912025-01-21T07:42:34ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902025-01-016110.1590/s2175-97902025e24422Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023Marx Ribeirohttps://orcid.org/0000-0003-3341-3605Juliana Cordeiro Cardosohttps://orcid.org/0000-0002-0357-4144José Eduardo Severino Martinshttps://orcid.org/0000-0002-3855-5701Aline Ferreira Pintohttps://orcid.org/0000-0003-2123-2284Eliana Maria Barbosa Soutohttps://orcid.org/0000-0002-9737-6017Patricia Severinohttps://orcid.org/0000-0001-6527-6612Abstract The landscape of scientific research in Latin America (LA), particularly in the realms of the Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutic models (PBPM), is a mosaic of varied contributions, collaborations, and specializations. This study examines research production in the region using data from the Scopus and PubMed databases collected between 2011 and 2023. Brazil stands out as a prominent country in terms of the quantity of publications. When considering thematic specialization, Colombia cones first as the country with the greatest Relative Specialization Index (RSI), followed by Brazil, Cuba, Uruguay, Mexico, and Argentina. Regarding internationalization, Brazil and Mexico are currently exerting significant influence, particularly through their increasing cooperation with the United States and Europe. Interestingly, there is a lack of cooperation inside Latin America at the regional level. Regarding the contribution of Latin-American institutions, the State University of Maringá leads in number of publications, followed by the University of São Paulo and the Federal University of São Paulo. In this work, we analyzed the strengths and weaknesses of LA’s scientific contributions, offering a roadmap for future collaborative and specialized efforts in the field of PBPK and PBBM.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502025000100808&lng=en&tlng=enPBPKPBBMLatin America Scientometric analysisInternational collaboration |
| spellingShingle | Marx Ribeiro Juliana Cordeiro Cardoso José Eduardo Severino Martins Aline Ferreira Pinto Eliana Maria Barbosa Souto Patricia Severino Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 Brazilian Journal of Pharmaceutical Sciences PBPK PBBM Latin America Scientometric analysis International collaboration |
| title | Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 |
| title_full | Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 |
| title_fullStr | Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 |
| title_full_unstemmed | Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 |
| title_short | Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023 |
| title_sort | physiologically based pharmacokinetic and physiologically based biopharmaceutic models research in latin america a regional level bibliometric analysis 2011 2023 |
| topic | PBPK PBBM Latin America Scientometric analysis International collaboration |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502025000100808&lng=en&tlng=en |
| work_keys_str_mv | AT marxribeiro physiologicallybasedpharmacokineticandphysiologicallybasedbiopharmaceuticmodelsresearchinlatinamericaaregionallevelbibliometricanalysis20112023 AT julianacordeirocardoso physiologicallybasedpharmacokineticandphysiologicallybasedbiopharmaceuticmodelsresearchinlatinamericaaregionallevelbibliometricanalysis20112023 AT joseeduardoseverinomartins physiologicallybasedpharmacokineticandphysiologicallybasedbiopharmaceuticmodelsresearchinlatinamericaaregionallevelbibliometricanalysis20112023 AT alineferreirapinto physiologicallybasedpharmacokineticandphysiologicallybasedbiopharmaceuticmodelsresearchinlatinamericaaregionallevelbibliometricanalysis20112023 AT elianamariabarbosasouto physiologicallybasedpharmacokineticandphysiologicallybasedbiopharmaceuticmodelsresearchinlatinamericaaregionallevelbibliometricanalysis20112023 AT patriciaseverino physiologicallybasedpharmacokineticandphysiologicallybasedbiopharmaceuticmodelsresearchinlatinamericaaregionallevelbibliometricanalysis20112023 |