The Specific Dermatoses of Pregnancy
Introduction and purpose: Pregnancy-specific dermatoses are a group of pruritic skin disorders that arise exclusively during pregnancy or the postpartum period. They encompass four primary conditions: atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP), intrahepatic cholesta...
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Nicolaus Copernicus University in Toruń
2025-02-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/58219 |
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| author | Paulina Polańska |
| author_facet | Paulina Polańska |
| author_sort | Paulina Polańska |
| collection | DOAJ |
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Introduction and purpose: Pregnancy-specific dermatoses are a group of pruritic skin disorders that arise exclusively during pregnancy or the postpartum period. They encompass four primary conditions: atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP), intrahepatic cholestasis of pregnancy (ICP), and pemphigoid gestationis (PG). This review aims to provide a comprehensive analysis of their prevalence, clinical characteristics, underlying mechanisms, therapeutic strategies, and potential fetal risks.
Results: These dermatoses often present with overlapping clinical features, making accurate differential diagnosis crucial. While some pose minimal risk to the fetus, others, such as ICP and PG, are associated with significant complications, including preterm birth and stillbirth. The underlying pathophysiology remains incompletely understood, with hormonal, immunological, genetic, and environmental factors playing key roles. Treatment strategies focus primarily on symptomatic relief, with topical corticosteroids and oral antihistamines being the mainstay of therapy, while ursodeoxycholic acid is the treatment of choice for ICP.
Conclusions: A multidisciplinary approach is essential for optimal maternal and fetal outcomes. Further research is needed to better understand the mechanisms and develop more effective treatment options for these conditions.
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| format | Article |
| id | doaj-art-a49ee81ba4274709a8e48cb4791eba4e |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-a49ee81ba4274709a8e48cb4791eba4e2025-02-06T08:24:40ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-02-013810.12775/QS.2024.38.58219The Specific Dermatoses of PregnancyPaulina Polańska0https://orcid.org/0009-0004-2365-79774th Military Clinical Hospital in Wroclaw, Weigla 5, 53-114 Wroclaw, Poland Introduction and purpose: Pregnancy-specific dermatoses are a group of pruritic skin disorders that arise exclusively during pregnancy or the postpartum period. They encompass four primary conditions: atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP), intrahepatic cholestasis of pregnancy (ICP), and pemphigoid gestationis (PG). This review aims to provide a comprehensive analysis of their prevalence, clinical characteristics, underlying mechanisms, therapeutic strategies, and potential fetal risks. Results: These dermatoses often present with overlapping clinical features, making accurate differential diagnosis crucial. While some pose minimal risk to the fetus, others, such as ICP and PG, are associated with significant complications, including preterm birth and stillbirth. The underlying pathophysiology remains incompletely understood, with hormonal, immunological, genetic, and environmental factors playing key roles. Treatment strategies focus primarily on symptomatic relief, with topical corticosteroids and oral antihistamines being the mainstay of therapy, while ursodeoxycholic acid is the treatment of choice for ICP. Conclusions: A multidisciplinary approach is essential for optimal maternal and fetal outcomes. Further research is needed to better understand the mechanisms and develop more effective treatment options for these conditions. https://apcz.umk.pl/QS/article/view/58219pregnancy-specific dermatosesatopic eruption of pregnancypolymorphic eruption of pregnancyintrahepatic cholestasis of pregnancypemphigoid gestationis |
| spellingShingle | Paulina Polańska The Specific Dermatoses of Pregnancy Quality in Sport pregnancy-specific dermatoses atopic eruption of pregnancy polymorphic eruption of pregnancy intrahepatic cholestasis of pregnancy pemphigoid gestationis |
| title | The Specific Dermatoses of Pregnancy |
| title_full | The Specific Dermatoses of Pregnancy |
| title_fullStr | The Specific Dermatoses of Pregnancy |
| title_full_unstemmed | The Specific Dermatoses of Pregnancy |
| title_short | The Specific Dermatoses of Pregnancy |
| title_sort | specific dermatoses of pregnancy |
| topic | pregnancy-specific dermatoses atopic eruption of pregnancy polymorphic eruption of pregnancy intrahepatic cholestasis of pregnancy pemphigoid gestationis |
| url | https://apcz.umk.pl/QS/article/view/58219 |
| work_keys_str_mv | AT paulinapolanska thespecificdermatosesofpregnancy AT paulinapolanska specificdermatosesofpregnancy |